Clinical outcome of peripheral nerve decompression in diabetic and nondiabetic peripheral neuropathy

Maria Siemionow*, Mohammed Alghoul, Michal Molski, Galip Agaoglu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Surgical decompression of peripheral nerves in patients with diabetes was reported to restore sensation and improve function. In this study, a retrospective review of 12 diabetic and 20 nondiabetic patients with lower-extremity peripheral neuropathy who underwent surgical decompression was performed. Clinical evaluation by Tinel test, muscle power examination, and 2-point discrimination were performed preoperatively, at 6 months, and between 9 and 15 months postdecompression. Clinical outcomes were classified into excellent, good, or fair based on improvement in symptoms and return of function. Thirty-two patients underwent 36 surgeries, in which 99 lower-extremity nerves were decompressed. There was a statistically significant improvement in muscle function (P < 0.001) and 2-point discrimination for the small toe (P = 0.008) and big toe (P = 0.038). At a mean of 7.7 months, 90% of patients showed significant improvement in pain and function. It is concluded that surgical decompression was associated with significant improvement in clinical outcome in patients with diabetic and idiopathic neuropathy with evidence of superimposed compression.

Original languageEnglish (US)
Pages (from-to)385-390
Number of pages6
JournalAnnals of plastic surgery
Issue number4
StatePublished - Oct 2006


  • Decompression
  • Diabetes
  • Lower extremity
  • Neuropathy

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Clinical outcome of peripheral nerve decompression in diabetic and nondiabetic peripheral neuropathy'. Together they form a unique fingerprint.

Cite this