Clinical Reasoning: A 77-Year-Old Man with Involuntary Movements, Sleep Changes, Falls, Bulbar Symptoms, and Cognitive Complaints

Toni Qian Cao; Glenn R. Harris; Christina M. Lineback; Leonard L. Sokol; Niccolo Mencacci; Puneet Opal

doi:10.1212/WNL.0000000000200705

Clinical Reasoning: A 77-Year-Old Man with Involuntary Movements, Sleep Changes, Falls, Bulbar Symptoms, and Cognitive Complaints

Toni Qian Cao^*, Glenn R. Harris, Christina M. Lineback, Leonard L. Sokol, Niccolo Mencacci, Puneet Opal

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A 77-year-old-man presents with chorea, parasomnias, dysarthria and dysphagia, and cognitive issues. A broad workup reveals positive anti-IgLON5 antibody. This case report represents a textbook example of anti-IgLON5 syndrome.

Original language	English (US)
Pages (from-to)	26-30
Number of pages	5
Journal	Neurology
Volume	99
Issue number	1
DOIs	https://doi.org/10.1212/WNL.0000000000200705
State	Published - Jul 5 2022

Funding

T. Cao, G. Harris, and C. Lineback report no relevant disclosures. L. Sokol is an ad hoc consultant for Tikvah for Parkinson and ad hoc consultant for the American Film Institute on end-of-life care/palliative care and receives financial support from the Northwestern PSTP Program in Neurology, the MSK R25 NCI 2R25CA190169, and the Huntington's Disease Society of America Center of Excellence (Grant ID: SP0070054). N. Mencacci reports no relevant disclosures. P. Opal receives support from the NIH (1R01NS082351). He has also received funding from the following sources for clinical trials: Biohaven Pharmaceuticals, NIH U01NS104326 (site PI), and the National Ataxia Foundation (CRC-SCA natural history study), as well as royalties from UpToDate. Go to Neurology.org/N for full disclosures.

ASJC Scopus subject areas

Clinical Neurology

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10.1212/WNL.0000000000200705

Cite this

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title = "Clinical Reasoning: A 77-Year-Old Man with Involuntary Movements, Sleep Changes, Falls, Bulbar Symptoms, and Cognitive Complaints",

abstract = "A 77-year-old-man presents with chorea, parasomnias, dysarthria and dysphagia, and cognitive issues. A broad workup reveals positive anti-IgLON5 antibody. This case report represents a textbook example of anti-IgLON5 syndrome.",

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AU - Mencacci, Niccolo

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Clinical Reasoning: A 77-Year-Old Man with Involuntary Movements, Sleep Changes, Falls, Bulbar Symptoms, and Cognitive Complaints

Abstract

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ASJC Scopus subject areas

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