Clinical Research in the United States at a Crossroads: Proposal for a Novel Public-Private Partnership to Establish a National Clinical Research Enterprise

William F. Crowley*, Louis Sherwood, Patricia Salber, David Scheinberg, Hal Slavkin, Hugh Tilson, E. Albert Reece, Veronica Catanese, Stephen B. Johnson, Adrian Dobs, Myron Genel, Allan Korn, Nancy Reame, Robert Bonow, Jack Grebb, David Rimoin

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

102 Scopus citations

Abstract

The clinical research infrastructure of the United States is currently at a critical crossroads. To leverage the enormous biomedical research gains made in the past century efficiently, a drastic need exists to reengineer this system into a coordinated, safe, and more efficient and effective enterprise. To accomplish this task, clinical research must be transformed from its current state as a cottage industry to an enterprise-wide health care pipeline whose function is to bring the novel research from both government and private entities to the US public. We propose the establishment of a unique public-private partnership termed the National Clinical Research Enterprise (NCRE). Its agenda should consist of informed public participation, supportive information technologies, a skilled workforce, and adequate funding in clinical research. Devoting only 0.25% of the budgets from all health care stakeholders to support the NCRE would permit adequate funding to build the infrastructure required to address these problems in an enterprise fashion. All participants in the US health care delivery system must come together to focus on system-wide improvements that will benefit the public.

Original languageEnglish (US)
Pages (from-to)1120-1126
Number of pages7
JournalJournal of the American Medical Association
Volume291
Issue number9
DOIs
StatePublished - Mar 3 2004

ASJC Scopus subject areas

  • Medicine(all)

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