Clinical Trial Design Considerations for Hospitalised Patients With Ulcerative Colitis Flares and Application to Study Hyperbaric Oxygen Therapy in the NIDDK HBOT-UC Consortium

Keyphrases

• Acute Severe 20%
• Baseline Testing 20%
• Bleeding Frequency 20%
• Bowel Movement 20%
• Care Delivery 20%
• Care Pathway 40%
• Clinical Trial Design 100%
• Clinical Trials 20%
• Confounding 20%
• Design Considerations 100%
• Design Methodology 20%
• Design Needs 20%
• Discharge Criteria 20%
• Disease Activity Score 20%
• Early Intervention 20%
• Endoscopy 20%
• Exclusion Criteria 20%
• Framework Decision 20%
• High Risk 20%
• Hospitalized Patients 100%
• Hyperbaric Oxygen 20%
• Hyperbaric Oxygen Therapy 100%
• Inclusion-exclusion 20%
• Late Intervention 20%
• Local Population 20%
• NIDDK 100%
• Novel Therapeutics 20%
• Patient-reported Outcomes 20%
• Postdischarge Follow-up 20%
• Pragmatic Trial Design 20%
• PRECIS-2 20%
• Rectal Bleeding 20%
• Remaining Gaps 20%
• Rescue Agents 20%
• Rescue Strategy 20%
• Secondary Measurement 20%
• Size Analysis 20%
• Small Clinical Trials 20%
• Standard of Care 20%
• Statistical Analysis Method 20%
• Statistical Considerations 20%
• Stool Frequency 20%
• Therapeutic Intervention 20%
• Trial Design 20%
• Ulcerative Colitis 100%
• Usual Care 20%
• Venous Thromboembolism Prophylaxis 20%

Medicine and Dentistry

• Care Pathway 66%
• Clinical Trial 33%
• Clinical Trial Design 100%
• Discharge Criterion 33%
• Disease Activity 33%
• Early Intervention 33%
• Endoscopy 33%
• Hyperbaric Medicine 100%
• Orphan 33%
• Patient with Ulcerative Colitis 100%
• Patient-Reported Outcome 33%
• Rectal Bleeding 33%
• Small Clinical Trial 33%
• Thromboprophylaxis 33%
• Ulcerative Colitis 100%