Clinical trials in HIV-associated cognitive impairment: Cognitive and functional outcomes

G. Schifitto; K. Kieburtz; M. P. McDermott; J. McArthur; K. Marder; N. Sacktor; D. Palumbo; O. Selnes; Y. Stern; L. Epstein; S. Albert

doi:10.1212/WNL.56.3.415

Clinical trials in HIV-associated cognitive impairment: Cognitive and functional outcomes

G. Schifitto^*, K. Kieburtz, M. P. McDermott, J. McArthur, K. Marder, N. Sacktor, D. Palumbo, O. Selnes, Y. Stern, L. Epstein, S. Albert

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Cognitive and functional outcomes are of primary interest in the design of efficacy trials in HIV-associated cognitive impairment. In a longitudinal cohort study, weak associations were found between measures of cognitive performance and commonly used measures of daily functioning (mostly self-report measures) in HIV-infected individuals. Modifications of current functional scales or new functional instruments are needed to assess the clinical relevance of cognitive changes in clinical trials of HIV-associated cognitive impairment.

Original language	English (US)
Pages (from-to)	415-418
Number of pages	4
Journal	Neurology
Volume	56
Issue number	3
DOIs	https://doi.org/10.1212/WNL.56.3.415
State	Published - Feb 13 2001

ASJC Scopus subject areas

Clinical Neurology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1212/WNL.56.3.415

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AU - McArthur, J.

AU - Marder, K.

AU - Sacktor, N.

AU - Palumbo, D.

AU - Selnes, O.

AU - Stern, Y.

AU - Epstein, L.

AU - Albert, S.

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Clinical trials in HIV-associated cognitive impairment: Cognitive and functional outcomes

Abstract

ASJC Scopus subject areas

UN SDGs

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