Clinical trials in HIV-associated cognitive impairment: Cognitive and functional outcomes

G. Schifitto*, K. Kieburtz, M. P. McDermott, J. McArthur, K. Marder, N. Sacktor, D. Palumbo, O. Selnes, Y. Stern, L. Epstein, S. Albert

*Corresponding author for this work

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Cognitive and functional outcomes are of primary interest in the design of efficacy trials in HIV-associated cognitive impairment. In a longitudinal cohort study, weak associations were found between measures of cognitive performance and commonly used measures of daily functioning (mostly self-report measures) in HIV-infected individuals. Modifications of current functional scales or new functional instruments are needed to assess the clinical relevance of cognitive changes in clinical trials of HIV-associated cognitive impairment.

Original languageEnglish (US)
Pages (from-to)415-418
Number of pages4
JournalNeurology
Volume56
Issue number3
DOIs
StatePublished - Feb 13 2001

ASJC Scopus subject areas

  • Clinical Neurology

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