TY - JOUR
T1 - Clonal t(8;14)(p11;q31) in a case of reactive lymphoproliferation
AU - Zhang, Yanming
AU - Schlegelberger, Brigitte
AU - Plendl, Hansjörg
AU - Sonnen, Ruth
AU - Kuse, Rolf
AU - Feller, Alfred C.
AU - Grote, Werner
PY - 1993/7
Y1 - 1993/7
N2 - A clone with an unbalanced translocation t(8;14)(p11;q31), resulting in deletion of the distal part of the long arm of chromosome 14, 14q31 → 14qter, was detected in a case of Piringer's lymphadenitis. Histopathologically no atypical cells or other signs of malignant lymphoma were found. Southern blot analyses showed no rearrangement of the immunoglobulin heavy chain gene (IGH) or the T‐cell receptor γ chain (TCRG) gene. The case exemplifies that the detection of a chromosomally aberrant clone does not necessarily prove that a lymphoproliferative process is malignant. © 1993 Wiley‐Liss, Inc.
AB - A clone with an unbalanced translocation t(8;14)(p11;q31), resulting in deletion of the distal part of the long arm of chromosome 14, 14q31 → 14qter, was detected in a case of Piringer's lymphadenitis. Histopathologically no atypical cells or other signs of malignant lymphoma were found. Southern blot analyses showed no rearrangement of the immunoglobulin heavy chain gene (IGH) or the T‐cell receptor γ chain (TCRG) gene. The case exemplifies that the detection of a chromosomally aberrant clone does not necessarily prove that a lymphoproliferative process is malignant. © 1993 Wiley‐Liss, Inc.
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U2 - 10.1002/gcc.2870070309
DO - 10.1002/gcc.2870070309
M3 - Article
C2 - 7687870
AN - SCOPUS:0027167693
SN - 1045-2257
VL - 7
SP - 165
EP - 168
JO - Genes, Chromosomes and Cancer
JF - Genes, Chromosomes and Cancer
IS - 3
ER -
