Cloning and characterization of a cDNA encoding the specific phosphatidylcholine transfer protein from bovine liver

David E. Cohen*, Richard M. Green

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

A 1917-bp cDNA clone encoding phosphatidylcholine transfer protein (PC-TP) was identified by screening a bovine liver library. Northern blot analysis demonstrated a 2-kb mRNA transcript in bovine liver, and Southern blotting was consistent with a single bovine PC-TP gene which was shown to be present in a diverse group of vertebrates, but not in yeast. Database comparisons revealed the nucleotide sequence of the clone to be unique and unrelated to other cytosolic lipid TP.

Original languageEnglish (US)
Pages (from-to)327-328
Number of pages2
JournalGene
Volume163
Issue number2
DOIs
StatePublished - Oct 3 1995

Keywords

  • Phospholipid
  • bile
  • bile salt
  • cholesterol
  • lipid transfer protein
  • membrane

ASJC Scopus subject areas

  • Genetics

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