Cloning and characterization of human pancreatic adenocarcinoma genes

D. M. Mahvi, R. S. Metzgar, O. J. Finn

Research output: Contribution to journalArticle

Abstract

Plasmids containing inserts representing pancreatic adenocarcinoma-specific genes have been isolated from a cDNA library. These genes are not amplified in the transformed genome and do not appear to be mutated. The level of transcription of one gene (2CF1) is increased in pancreatic adenocarcinoma, but not in the normal adult pancreas, or PBL. The protein product of this differentially expressed gene may be related to malignant transformation in pancreatic adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)385-387
Number of pages3
JournalSurgical Forum
VolumeVOL. 36
StatePublished - Jan 1 1985

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Organism Cloning
Adenocarcinoma
Genes
Gene Library
Pancreas
Plasmids
Genome
Proteins

ASJC Scopus subject areas

  • Surgery

Cite this

Mahvi, D. M., Metzgar, R. S., & Finn, O. J. (1985). Cloning and characterization of human pancreatic adenocarcinoma genes. Surgical Forum, VOL. 36, 385-387.
Mahvi, D. M. ; Metzgar, R. S. ; Finn, O. J. / Cloning and characterization of human pancreatic adenocarcinoma genes. In: Surgical Forum. 1985 ; Vol. VOL. 36. pp. 385-387.
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Mahvi, DM, Metzgar, RS & Finn, OJ 1985, 'Cloning and characterization of human pancreatic adenocarcinoma genes', Surgical Forum, vol. VOL. 36, pp. 385-387.

Cloning and characterization of human pancreatic adenocarcinoma genes. / Mahvi, D. M.; Metzgar, R. S.; Finn, O. J.

In: Surgical Forum, Vol. VOL. 36, 01.01.1985, p. 385-387.

Research output: Contribution to journalArticle

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Mahvi DM, Metzgar RS, Finn OJ. Cloning and characterization of human pancreatic adenocarcinoma genes. Surgical Forum. 1985 Jan 1;VOL. 36:385-387.