Abstract
Plasmids containing inserts representing pancreatic adenocarcinoma-specific genes have been isolated from a cDNA library. These genes are not amplified in the transformed genome and do not appear to be mutated. The level of transcription of one gene (2CF1) is increased in pancreatic adenocarcinoma, but not in the normal adult pancreas, or PBL. The protein product of this differentially expressed gene may be related to malignant transformation in pancreatic adenocarcinoma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 385-387 |
| Number of pages | 3 |
| Journal | Surgical Forum |
| Volume | VOL. 36 |
| State | Published - Jan 1 1985 |
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ASJC Scopus subject areas
- Surgery
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Cloning and characterization of human pancreatic adenocarcinoma genes. / Mahvi, D. M.; Metzgar, R. S.; Finn, O. J.
In: Surgical Forum, Vol. VOL. 36, 01.01.1985, p. 385-387.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cloning and characterization of human pancreatic adenocarcinoma genes
AU - Mahvi, D. M.
AU - Metzgar, R. S.
AU - Finn, O. J.
PY - 1985/1/1
Y1 - 1985/1/1
N2 - Plasmids containing inserts representing pancreatic adenocarcinoma-specific genes have been isolated from a cDNA library. These genes are not amplified in the transformed genome and do not appear to be mutated. The level of transcription of one gene (2CF1) is increased in pancreatic adenocarcinoma, but not in the normal adult pancreas, or PBL. The protein product of this differentially expressed gene may be related to malignant transformation in pancreatic adenocarcinoma.
AB - Plasmids containing inserts representing pancreatic adenocarcinoma-specific genes have been isolated from a cDNA library. These genes are not amplified in the transformed genome and do not appear to be mutated. The level of transcription of one gene (2CF1) is increased in pancreatic adenocarcinoma, but not in the normal adult pancreas, or PBL. The protein product of this differentially expressed gene may be related to malignant transformation in pancreatic adenocarcinoma.
UR - http://www.scopus.com/inward/record.url?scp=0022357992&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022357992&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0022357992
VL - VOL. 36
SP - 385
EP - 387
JO - Surgical Forum
JF - Surgical Forum
SN - 0071-8041
ER -