Phosphatidylcholine transfer protein (PC-TP) is a cytosolic protein that catalyzes intermembrane transfer of phosphatidylcholines in vitro. We have cloned a cDNA encoding the human ortholog of PC-TP and have determined its tissue-specific expression as well as genomic organization. Radiation hybrid mapping localized the human gene, PCTP, to chromosome 17q21-22 and PCR-based single strand conformation polymorphism analysis of an interspecific backcross assigned mouse Pctp to the region of syntenic conservation on chromosome 11. Copyright (C) 1999 Elsevier Science B.V.
|Original language||English (US)|
|Number of pages||6|
|Journal||Biochimica et Biophysica Acta - Gene Structure and Expression|
|State||Published - Oct 28 1999|
- Transfer Protein
ASJC Scopus subject areas
- Structural Biology