Coasting after overpressure induction with sevoflurane

Jan F A Hendrickx, Dirk M. Vandeput, Axel M. De Geyndt, Thierry Deloof, Andre M. De Wolf

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Study Objective: To evaluate the clinical feasibility of using a coasting technique to temporarily maintain anesthesia after overpressure induction with sevoflurane.Study Design: Prospective clinical study.Setting: Large teaching hospital.Patients: 12 ASA physical status I, II, and III patients receiving general anesthesia for a variety of peripheral procedures.Interventions: After overpressure induction of anesthesia with sevoflurane (8%) in an O2/N2O mixture, the fresh gas flow (FGF) was lowered to 0.5 L/min and the vaporizer was turned off (coasting).Measurements and Main Results: After priming a circle system with sevoflurane (8% sevoflurane vaporizer setting in 6 L/min O2/N2O [33%/66%] for 30 s), patients took several vital capacity breaths from the mixture until loss of consciousness. After 3.4 ± 0.7 min, depth of anesthesia was considered adequate for laryngeal mask airway (LMA) insertion, and FGF was reduced to 0.5 L/min (33% O2, 66% N2O) and the sevoflurane vaporizer was turned off. The end-expired sevoflurane concentration (Et(sevo)) decreased from 5.8 ± 1.3% just before insertion of the LMA to 0.97 ± 0.22% at 20 minutes.Conclusions: After overpressure induction with sevoflurane, coasting during minimal flow anesthesia (FGF 0.5 L/min) is a simple technique that can maintain anesthesia for short procedures (less than 15 to 20 min), or can be used as a bridge or an adjunct to other low-flow techniques.

Original languageEnglish (US)
Pages (from-to)100-103
Number of pages4
JournalJournal of Clinical Anesthesia
Issue number2
StatePublished - Mar 2000


  • Anesthetic techniques
  • Anesthetics
  • Coasting
  • Minimal flow anesthesia
  • Pharmacokinetics of
  • Sevoflurane
  • Volatile

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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