Cohabitation with a Known Coronavirus Disease 2019 Case Is Associated with Greater Antibody Concentration and Symptom Severity in a Community-Based Sample of Seropositive Adults

Joshua M. Schrock, Daniel T. Ryan, Rana Saber, Nanette Benbow, Lauren A. Vaught, Nina Reiser, Matthew P. Velez, Ryan Hsieh, Michael Newcomb, Alexis R. Demonbreun, Brian Mustanski, Elizabeth M. McNally, Richard D'Aquila, Thomas W. McDade

Research output: Contribution to journalArticlepeer-review

Abstract

In a community-based sample of seropositive adults (n=1101), we found that seropositive individuals who lived with a known coronavirus disease 2019 (COVID-19) case exhibited higher blood anti-severe acute respiratory syndrome coronavirus 2 spike receptor-binding domain immunoglobulin G concentrations and greater symptom severity compared to seropositive individuals who did not live with a known COVID-19 case.

Original languageEnglish (US)
Article numberofab244
JournalOpen Forum Infectious Diseases
Volume8
Issue number7
DOIs
StatePublished - Jul 2021

Keywords

  • immunity
  • severe acute respiratory syndrome coronavirus 2
  • transmission

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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