Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract

Hiroyuki Tsujino, Michael Jones, Jian Xin Qin, Marta Sitges, Lisa A. Cardon, Annitta L. Morehead, Arthur D. Zetts, Fabrice Bauer, Yong Jin Kim, Xi Yi Hang, Neil Greenberg, James D. Thomas, Takahiro Shiota

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Real-time three-dimensional (3-D) color Doppler echocardiography (RT3D) is capable of quantifying flow. However, low temporal resolution limits its application to stroke volume (SV) measurements. The aim of the present study was, therefore, to develop a reliable method to quantify SV. In animal experiments, cross-sectional images of the LV outflow tract were selected from the RT3D data to calculate peak flow rates (Q p3D). Conventional pulsed-wave (PW) Doppler was performed to measure the velocity-time integral (VTI) and the peak velocity (V p). By assuming that the flow is proportional to the velocity temporal waveform, SV was calculated as α × Q p3D × VTI/V p, where α is a temporal correction factor. There was an excellent correlation between the reference flow meter and RT3D SV (mean difference = -1. 3 mL, y = 1. 05x -2. 5, r = 0. 94, p < 0. 01). The new method allowed accurate SV estimations without any geometric assumptions of the spatial velocity distributions. (E-mail: shiotat@ccf.org)

Original languageEnglish (US)
Pages (from-to)1441-1446
Number of pages6
JournalUltrasound in Medicine and Biology
Volume30
Issue number11
DOIs
StatePublished - Nov 1 2004

Keywords

  • 3-D echocardiography
  • Color Doppler
  • Doppler ultrasound
  • Hemodynamics

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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