Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract

Hiroyuki Tsujino; Michael Jones; Jian Xin Qin; Marta Sitges; Lisa A. Cardon; Annitta L. Morehead; Arthur D. Zetts; Fabrice Bauer; Yong Jin Kim; Xi Yi Hang; Neil Greenberg; James D. Thomas; Takahiro Shiota

doi:10.1016/j.ultrasmedbio.2004.08.027

Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract

Hiroyuki Tsujino, Michael Jones, Jian Xin Qin, Marta Sitges, Lisa A. Cardon, Annitta L. Morehead, Arthur D. Zetts, Fabrice Bauer, Yong Jin Kim, Xi Yi Hang, Neil Greenberg, James D. Thomas, Takahiro Shiota

Medicine, Cardiology Division

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Real-time three-dimensional (3-D) color Doppler echocardiography (RT3D) is capable of quantifying flow. However, low temporal resolution limits its application to stroke volume (SV) measurements. The aim of the present study was, therefore, to develop a reliable method to quantify SV. In animal experiments, cross-sectional images of the LV outflow tract were selected from the RT3D data to calculate peak flow rates (Q _p3D). Conventional pulsed-wave (PW) Doppler was performed to measure the velocity-time integral (VTI) and the peak velocity (V _p). By assuming that the flow is proportional to the velocity temporal waveform, SV was calculated as α × Q _p3D × VTI/V _p, where α is a temporal correction factor. There was an excellent correlation between the reference flow meter and RT3D SV (mean difference = -1. 3 mL, y = 1. 05x -2. 5, r = 0. 94, p < 0. 01). The new method allowed accurate SV estimations without any geometric assumptions of the spatial velocity distributions. (E-mail: [email protected])

Original language	English (US)
Pages (from-to)	1441-1446
Number of pages	6
Journal	Ultrasound in Medicine and Biology
Volume	30
Issue number	11
DOIs	https://doi.org/10.1016/j.ultrasmedbio.2004.08.027
State	Published - Nov 2004

Funding

The authors acknowledge the assistance of the veterinary professional and technical staff of the Laboratory of Animal Medicine and Surgery, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland. This study was supported in part by the National Aeronautics and Space Administration, Houston, Texas (grand NCC9-58), and by “Grant-in-Aid” American Heart Association, Oregon Affiliate and Ohio Valley Affiliate.

Keywords

3-D echocardiography
Color Doppler
Doppler ultrasound
Hemodynamics

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Biophysics
Acoustics and Ultrasonics

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10.1016/j.ultrasmedbio.2004.08.027

Cite this

Tsujino, H., Jones, M., Qin, J. X., Sitges, M., Cardon, L. A., Morehead, A. L., Zetts, A. D., Bauer, F., Kim, Y. J., Hang, X. Y., Greenberg, N., Thomas, J. D., & Shiota, T. (2004). Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract. Ultrasound in Medicine and Biology, 30(11), 1441-1446. https://doi.org/10.1016/j.ultrasmedbio.2004.08.027

@article{f0dfff02efd34a6db3f9735220a1768c,

title = "Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract",

abstract = "Real-time three-dimensional (3-D) color Doppler echocardiography (RT3D) is capable of quantifying flow. However, low temporal resolution limits its application to stroke volume (SV) measurements. The aim of the present study was, therefore, to develop a reliable method to quantify SV. In animal experiments, cross-sectional images of the LV outflow tract were selected from the RT3D data to calculate peak flow rates (Q p3D). Conventional pulsed-wave (PW) Doppler was performed to measure the velocity-time integral (VTI) and the peak velocity (V p). By assuming that the flow is proportional to the velocity temporal waveform, SV was calculated as α × Q p3D × VTI/V p, where α is a temporal correction factor. There was an excellent correlation between the reference flow meter and RT3D SV (mean difference = -1. 3 mL, y = 1. 05x -2. 5, r = 0. 94, p < 0. 01). The new method allowed accurate SV estimations without any geometric assumptions of the spatial velocity distributions. (E-mail: [email protected])",

keywords = "3-D echocardiography, Color Doppler, Doppler ultrasound, Hemodynamics",

author = "Hiroyuki Tsujino and Michael Jones and Qin, {Jian Xin} and Marta Sitges and Cardon, {Lisa A.} and Morehead, {Annitta L.} and Zetts, {Arthur D.} and Fabrice Bauer and Kim, {Yong Jin} and Hang, {Xi Yi} and Neil Greenberg and Thomas, {James D.} and Takahiro Shiota",

note = "Funding Information: The authors acknowledge the assistance of the veterinary professional and technical staff of the Laboratory of Animal Medicine and Surgery, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland. This study was supported in part by the National Aeronautics and Space Administration, Houston, Texas (grand NCC9-58), and by “Grant-in-Aid” American Heart Association, Oregon Affiliate and Ohio Valley Affiliate.",

year = "2004",

month = nov,

doi = "10.1016/j.ultrasmedbio.2004.08.027",

language = "English (US)",

volume = "30",

pages = "1441--1446",

journal = "Ultrasound in Medicine and Biology",

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Tsujino, H, Jones, M, Qin, JX, Sitges, M, Cardon, LA, Morehead, AL, Zetts, AD, Bauer, F, Kim, YJ, Hang, XY, Greenberg, N, Thomas, JD & Shiota, T 2004, 'Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract', Ultrasound in Medicine and Biology, vol. 30, no. 11, pp. 1441-1446. https://doi.org/10.1016/j.ultrasmedbio.2004.08.027

Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract. / Tsujino, Hiroyuki; Jones, Michael; Qin, Jian Xin et al.
In: Ultrasound in Medicine and Biology, Vol. 30, No. 11, 11.2004, p. 1441-1446.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract

AU - Tsujino, Hiroyuki

AU - Jones, Michael

AU - Qin, Jian Xin

AU - Sitges, Marta

AU - Cardon, Lisa A.

AU - Morehead, Annitta L.

AU - Zetts, Arthur D.

AU - Bauer, Fabrice

AU - Kim, Yong Jin

AU - Hang, Xi Yi

AU - Greenberg, Neil

AU - Thomas, James D.

AU - Shiota, Takahiro

N1 - Funding Information: The authors acknowledge the assistance of the veterinary professional and technical staff of the Laboratory of Animal Medicine and Surgery, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland. This study was supported in part by the National Aeronautics and Space Administration, Houston, Texas (grand NCC9-58), and by “Grant-in-Aid” American Heart Association, Oregon Affiliate and Ohio Valley Affiliate.

PY - 2004/11

Y1 - 2004/11

N2 - Real-time three-dimensional (3-D) color Doppler echocardiography (RT3D) is capable of quantifying flow. However, low temporal resolution limits its application to stroke volume (SV) measurements. The aim of the present study was, therefore, to develop a reliable method to quantify SV. In animal experiments, cross-sectional images of the LV outflow tract were selected from the RT3D data to calculate peak flow rates (Q p3D). Conventional pulsed-wave (PW) Doppler was performed to measure the velocity-time integral (VTI) and the peak velocity (V p). By assuming that the flow is proportional to the velocity temporal waveform, SV was calculated as α × Q p3D × VTI/V p, where α is a temporal correction factor. There was an excellent correlation between the reference flow meter and RT3D SV (mean difference = -1. 3 mL, y = 1. 05x -2. 5, r = 0. 94, p < 0. 01). The new method allowed accurate SV estimations without any geometric assumptions of the spatial velocity distributions. (E-mail: [email protected])

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KW - 3-D echocardiography

KW - Color Doppler

KW - Doppler ultrasound

KW - Hemodynamics

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ER -

Combination of pulsed-wave Doppler and real-time three-dimensional color Doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract

Abstract

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Keywords

ASJC Scopus subject areas

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