Combined time-resolved and high-spatial-resolution 3D MRA using an extended adaptive acquisition

Yousef Mazaheri*, Timothy J. Carroll, Jiang Du, Walter F. Block, Sean B. Fain, Thomas F. Hany, Beverly D L Aagaard, Charles M. Strother, Charles A. Mistretta, Thomas M. Grist

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Purpose: To combine the benefits of time-resolved dynamic imaging and single elliptical centric acquisitions in a reasonable scan time. Materials and Methods: A time series of images with moderate spatial resolution was acquired using the 3D Time-Resolved Imaging of Contrast Kinetics (3D TRICKS) technique with elliptical centric encoding during contrast arrival. Following venous opacification, a complete large centrically encoded k-space volume was acquired. The high-spatial-frequency portions of this volume were combined with a 3D TRICKS time frame to form a high-resolution image. An additional single image is formed by suppressing background and signal averaging all acquired data, including post-venous low-spatial-frequency data. For this image, 2D temporal correlation analysis is used to suppress low-spatial-frequency vein contributions. Arrival time and spatial correlations are used to suppress background. Results: The 3D TRICKS time frame may be selected to ensure a combined high-resolution image that has optimal central k-space sampling for any vascular region. The single image formed by signal averaging all acquired data has increased contrast-to-noise (CNR) and signal-to-noise (SNR) ratios. Conclusion: The advantages of time-resolved and high-spatial-resolution imaging were combined using an extended dual-phase acquisition. Some SNR and CNR gain was achieved by signal averaging. This process is facilitated by background and vein suppression.

Original languageEnglish (US)
Pages (from-to)291-301
Number of pages11
JournalJournal of Magnetic Resonance Imaging
Issue number3
StatePublished - 2002


  • High resolution 3D MRA
  • Intravascular contrast material
  • Time-resolved acquisition

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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