Isolated comma or corkscrew shaped venular segments in the conjunctiva have been felt to be diagnostic of sickle cell disease. External eye examination of a 34 year old black man with a two year history of chronic granulocytic leukemia revealed multiple small and medium sized isolated conjunctival venular segments. Laboratory findings at the time of examination included a white blood cell count of 132,000/mm3 with 87% eosinophils, a hematocrit reading of 30%, and hemoglobin AA. Since whole blood hyperviscosity can be present in chronic granulocytic leukemia as well as sickle cell disease, this may account for the similarity of the conjunctival changes.
|Original language||English (US)|
|Number of pages||4|
|Journal||Canadian Journal of Ophthalmology|
|State||Published - Dec 1 1975|
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