Comment on Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase

John W. Peters*, Oliver Einsle*, Dennis R. Dean, Serena DeBeer, Brian M. Hoffman, Patrick L. Holland, Lance C. Seefeldt

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations

Abstract

Kang et al. (Reports, 19 June 2020, p. 1381) report a structure of the nitrogenase MoFe protein that is interpreted to indicate binding of N2 or an N2-derived species to the active-site FeMo cofactor. Independent refinement of the structure and consideration of biochemical evidence do not support this claim.

Original languageEnglish (US)
Article numbereabe5481
JournalScience
Volume371
Issue number6530
DOIs
StatePublished - Feb 12 2021

ASJC Scopus subject areas

  • General

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