TY - JOUR
T1 - Comorbidities and the impact of atopic dermatitis
AU - Silverberg, Jonathan I.
N1 - Funding Information:
Disclosures: Dr. Silverberg served as a consultant or advisory board member for Abbvie, Asana, Eli Lilly, Galderma, GlaxoSmithKline, Glenmark, Incyte, Kiniksa, Leo, Menlo, Pfizer, Regeneron-Sanofi, Realm, and Dermavant, receiving honoraria; speaker for Regeneron-Sanofi; and received research grants from GlaxoSmithKline and Galderma.
Publisher Copyright:
© 2019 American College of Allergy, Asthma & Immunology
PY - 2019/8
Y1 - 2019/8
N2 - Objective: Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial patient and population burdens. A number of comorbid health problems occur in patients with AD, aside from the cutaneous signs and symptoms. This review summarizes recent developments in the burden and comorbidities of AD. Data Sources: Literature review. Study Selections: Nonsystematic. Results: Different aspects of AD, such as chronic pruritus, psychosocial distress, and inflammation, can lead to anxiety, depression, or suicidality. Atopic dermatitis is associated with and may predispose to higher risk of other atopic disorders, including asthma, hay fever, food allergy, and eosinophilic esophagitis. Persons with AD appear to be at higher risk for infectious and cardiovascular risk. Conclusion: Atopic dermatitis is associated with substantial burden and comorbidities. Identifying AD comorbidities is essential for proper disease management and improving overall patient outcomes.
AB - Objective: Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with substantial patient and population burdens. A number of comorbid health problems occur in patients with AD, aside from the cutaneous signs and symptoms. This review summarizes recent developments in the burden and comorbidities of AD. Data Sources: Literature review. Study Selections: Nonsystematic. Results: Different aspects of AD, such as chronic pruritus, psychosocial distress, and inflammation, can lead to anxiety, depression, or suicidality. Atopic dermatitis is associated with and may predispose to higher risk of other atopic disorders, including asthma, hay fever, food allergy, and eosinophilic esophagitis. Persons with AD appear to be at higher risk for infectious and cardiovascular risk. Conclusion: Atopic dermatitis is associated with substantial burden and comorbidities. Identifying AD comorbidities is essential for proper disease management and improving overall patient outcomes.
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U2 - 10.1016/j.anai.2019.04.020
DO - 10.1016/j.anai.2019.04.020
M3 - Review article
C2 - 31034875
AN - SCOPUS:85066780863
SN - 1081-1206
VL - 123
SP - 144
EP - 151
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
IS - 2
ER -
