Comparative studies on citric acid production by Aspergillus niger and Candida lipolytica using molasses and glucose

M. Pazouki, P. A. Felse, J. Sinha, T. Panda*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Citric acid production by Aspergillus niger NCIM 548 and Candida lipolytica NCIM 3472 has been studied in shake culture using glucose and molasses as carbon sources. Methanol addition (3% v/v) at 40 h of fermentation enhanced the production of citric acid by Aspergillus niger whereas a reduction in citric acid production by Candida lipolytica was observed with addition of methanol. Maximum citric acid concentration of 12 kg/m3 was obtained with Aspergillus niger using molasses in the presence of methanol, while maximum citric acid concentration of 8.4 kg/m3 was obtained with Candida lipolytica using glucose without methanol. It appears that product formation by Aspergillus niger is either non-growth associated or partially growth associated depending on the substrate. Methanol addition changes the nature of product formation in case of Candida lipolytica.

Original languageEnglish (US)
Pages (from-to)353-361
Number of pages9
JournalBioprocess Engineering
Volume22
Issue number4
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

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