Comparison of inpatients with major mental illness who do and do not consent to low-risk research

George E. Jaskiw*, Tim E. Blumer, Rolando Gutierrez-Esteinou, Herbert Y. Meltzer, Vickie Steele, Milton E. Strauss

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The generalizability of research data depends on the degree to which the studied sample represents the larger population of interest. By influencing the likelihood of research participation, socio-demographic and clinical factors could bias a sample. To evaluate this, we retrospectively identified 155 consecutive admissions over an 18-month period to a general acute male psychiatry inpatient unit in a Veterans Affairs Hospital on which all competent patients were offered the opportunity to participate in low-risk clinical research. Male inpatients who did (N=70) and did not consent (N=85) were compared on 17 variables. Patients who consented to research were somewhat younger (Mdifference=4.6 year) and were significantly more likely to carry a diagnosis of schizophrenia. The groups did not differ in financial resources, living situation or alcohol/drug abuse. We conclude that at least in this setting, general socio-demographic and clinical variables were not major influences on sample selection.

Original languageEnglish (US)
Pages (from-to)183-188
Number of pages6
JournalPsychiatry Research
Issue number1-2
StatePublished - Jul 15 2003


  • Age
  • Sampling
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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