Comparison of left ventricular stroke volume determination by real-time three-dimensional echocardiography and conventional two-dimensional echocardiography: An animal study during non-ischemic and ischemic conditions

J. X. Qin, M. Jones, T. Shiota*, N. L. Greenberg, L. A. Cardon, A. D. Zetts, H. Tsujino, J. D. Thomas

*Corresponding author for this work

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Recently, 3D echocardiography (3DE) has developed the capability to capture 3D images in real-time and has been reported to be accurate for estimating left ventricular (LV) volume. We hypothesized that real-time 3DE could determine LV stroke volumes (SV) more accurately than conventional 2DE. Purpose: The aim of this study was to compare 2DE and 3DE for estimating LV stroke volumes during a variety of hemodynamic conditions, including left anterior descending (LAD) coronary artery occlusions. Methods: During a total of 30 hemodynamic conditions in 6 sheep with chronic aortic regurgitation, electromagnetic (EM) flow probes and meters were used to obtain LV SV. LV end-diastolic (LV EDV) and LV end-systolic volumes (LV ESV) were measured using real-time 3DE with Simpson's rule (slice spacing 7 mm). Results: For 24 conditions without LAD occlusions, SV by EM ranged from 27 to 66 ml (average 45±10ml). The correlation for LV SV measured by 3DE and that by EM was excellent (r = 0.92, y = 0.91x + 3.6, Δ = -1±4 ml, n = 24), and better than that between 2DE and EM (r = 0.62, y= 0.68x + 8.8, Δ= -5.6 ± 9.4 ml, p = 0.0003). For 6 conditions during LAD occlusion, SV by EM ranged from 26 to 58 ml (average 41 ± 12ml). SV derived from 3DE also agreed well with values derived by EM (r = 0.96); however, the r-value between 2DE and EM was reduced to 0.58. Conclusion: Real-time 3DE provided accurate assessment of LV SV under both ischemic and nonischemic conditions, while conventional 2DE showed poor correlations with reference standards, especially for SVs during coronary artery occlusion.

Original languageEnglish (US)
Pages (from-to)645-648
Number of pages4
JournalComputers in Cardiology
Volume0
Issue number0
StatePublished - Dec 1 1998

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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