Comparison of three biphasic defibrillation waveforms: Gurvich waveform is more efficient

F. Qu*, V. P. Nikolski, B. R. Wollenzier, I. R. Efimov

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations

Abstract

Biphasic waveform has greater defibrillation efficacy than monophasic waveform. Yet, the optimal type of biphasic defibrillation waveform is still unknown. Our objective was to compare the defibrillation efficacy of three morphologically different biphasic waveforms (named as truncated exponential waveform, modified Zoll waveform, and Gurvich waveform) in isolated Langendorff perfused rabbit heart. Optical potential mapping techniques were used. The result showed that, Gurvich waveform has the lowest defibrillation threshold (DFT). Multiple comparison test showed that there is a significant difference of DFTs between modified Zoll waveform and Gurvich waveform (Mean±SE: 0.31±0.03 J and 0.25±0.02 J, p<0.02). We also examined the change of membrane potential caused by shocks. The result showed homogeneous response for different waveforms.

Original languageEnglish (US)
Pages (from-to)1439-1440
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
StatePublished - 2002
Externally publishedYes
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Defibrillation waveform
  • Electrophysiology
  • Heart

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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