Complementary and Alternative Medicine for Atopic Dermatitis

An Evidence-Based Review

Brittany L. Vieira, Neil R. Lim, Mary E. Lohman, Peter A Lio*

*Corresponding author for this work

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

Background: Complementary and alternative interventions are becoming increasingly utilized as adjuncts to conventional treatment of atopic dermatitis (AD). While the number of studies continues to grow, the vastness of the subject coupled with the relatively poor quality and small size of the studies limit their usefulness to clinicians. Purpose: Our aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD. Methods: Searches were performed on PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and the Global Resource for EczemA Trial (GREAT) databases, focusing on RCTs of alternative or complementary AD therapies, with a sample size of ≥10, through March 2015 and limited to the English language. A total of 70 manuscripts met the inclusion criteria and were included in the final analysis. Results: There is at least some level I evidence to support the use of acupuncture and acupressure, stress-reducing techniques such as hypnosis, massage, and biofeedback, balneotherapy, herbal preparations (with many important caveats), certain botanical oils, oral evening primrose oil, vitamin D supplementation, and topical vitamin B12. Many other therapies either have sufficient data to suggest that they are ineffective, or simply do not have enough evidence to formulate a verdict. Conclusions: Careful review of the literature reveals several promising therapies in this domain; such findings may help direct further research that is necessary to bolster clinical recommendations for alternative or complementary treatments of AD.

Original languageEnglish (US)
Pages (from-to)557-581
Number of pages25
JournalAmerican Journal of Clinical Dermatology
Volume17
Issue number6
DOIs
StatePublished - Dec 1 2016

Fingerprint

Atopic Dermatitis
Complementary Therapies
Randomized Controlled Trials
Acupressure
Balneology
Plant Preparations
Therapeutics
Massage
Hypnosis
Manuscripts
Eczema
Acupuncture
Vitamin B 12
PubMed
Vitamin D
Sample Size
Oils
Language
Databases
Research

ASJC Scopus subject areas

  • Dermatology

Cite this

Vieira, Brittany L. ; Lim, Neil R. ; Lohman, Mary E. ; Lio, Peter A. / Complementary and Alternative Medicine for Atopic Dermatitis : An Evidence-Based Review. In: American Journal of Clinical Dermatology. 2016 ; Vol. 17, No. 6. pp. 557-581.
@article{0a6ec2ce08d54a768ff54e6f26097efe,
title = "Complementary and Alternative Medicine for Atopic Dermatitis: An Evidence-Based Review",
abstract = "Background: Complementary and alternative interventions are becoming increasingly utilized as adjuncts to conventional treatment of atopic dermatitis (AD). While the number of studies continues to grow, the vastness of the subject coupled with the relatively poor quality and small size of the studies limit their usefulness to clinicians. Purpose: Our aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD. Methods: Searches were performed on PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and the Global Resource for EczemA Trial (GREAT) databases, focusing on RCTs of alternative or complementary AD therapies, with a sample size of ≥10, through March 2015 and limited to the English language. A total of 70 manuscripts met the inclusion criteria and were included in the final analysis. Results: There is at least some level I evidence to support the use of acupuncture and acupressure, stress-reducing techniques such as hypnosis, massage, and biofeedback, balneotherapy, herbal preparations (with many important caveats), certain botanical oils, oral evening primrose oil, vitamin D supplementation, and topical vitamin B12. Many other therapies either have sufficient data to suggest that they are ineffective, or simply do not have enough evidence to formulate a verdict. Conclusions: Careful review of the literature reveals several promising therapies in this domain; such findings may help direct further research that is necessary to bolster clinical recommendations for alternative or complementary treatments of AD.",
author = "Vieira, {Brittany L.} and Lim, {Neil R.} and Lohman, {Mary E.} and Lio, {Peter A}",
year = "2016",
month = "12",
day = "1",
doi = "10.1007/s40257-016-0209-1",
language = "English (US)",
volume = "17",
pages = "557--581",
journal = "American Journal of Clinical Dermatology",
issn = "1175-0561",
publisher = "Adis International Ltd",
number = "6",

}

Complementary and Alternative Medicine for Atopic Dermatitis : An Evidence-Based Review. / Vieira, Brittany L.; Lim, Neil R.; Lohman, Mary E.; Lio, Peter A.

In: American Journal of Clinical Dermatology, Vol. 17, No. 6, 01.12.2016, p. 557-581.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Complementary and Alternative Medicine for Atopic Dermatitis

T2 - An Evidence-Based Review

AU - Vieira, Brittany L.

AU - Lim, Neil R.

AU - Lohman, Mary E.

AU - Lio, Peter A

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background: Complementary and alternative interventions are becoming increasingly utilized as adjuncts to conventional treatment of atopic dermatitis (AD). While the number of studies continues to grow, the vastness of the subject coupled with the relatively poor quality and small size of the studies limit their usefulness to clinicians. Purpose: Our aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD. Methods: Searches were performed on PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and the Global Resource for EczemA Trial (GREAT) databases, focusing on RCTs of alternative or complementary AD therapies, with a sample size of ≥10, through March 2015 and limited to the English language. A total of 70 manuscripts met the inclusion criteria and were included in the final analysis. Results: There is at least some level I evidence to support the use of acupuncture and acupressure, stress-reducing techniques such as hypnosis, massage, and biofeedback, balneotherapy, herbal preparations (with many important caveats), certain botanical oils, oral evening primrose oil, vitamin D supplementation, and topical vitamin B12. Many other therapies either have sufficient data to suggest that they are ineffective, or simply do not have enough evidence to formulate a verdict. Conclusions: Careful review of the literature reveals several promising therapies in this domain; such findings may help direct further research that is necessary to bolster clinical recommendations for alternative or complementary treatments of AD.

AB - Background: Complementary and alternative interventions are becoming increasingly utilized as adjuncts to conventional treatment of atopic dermatitis (AD). While the number of studies continues to grow, the vastness of the subject coupled with the relatively poor quality and small size of the studies limit their usefulness to clinicians. Purpose: Our aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD. Methods: Searches were performed on PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and the Global Resource for EczemA Trial (GREAT) databases, focusing on RCTs of alternative or complementary AD therapies, with a sample size of ≥10, through March 2015 and limited to the English language. A total of 70 manuscripts met the inclusion criteria and were included in the final analysis. Results: There is at least some level I evidence to support the use of acupuncture and acupressure, stress-reducing techniques such as hypnosis, massage, and biofeedback, balneotherapy, herbal preparations (with many important caveats), certain botanical oils, oral evening primrose oil, vitamin D supplementation, and topical vitamin B12. Many other therapies either have sufficient data to suggest that they are ineffective, or simply do not have enough evidence to formulate a verdict. Conclusions: Careful review of the literature reveals several promising therapies in this domain; such findings may help direct further research that is necessary to bolster clinical recommendations for alternative or complementary treatments of AD.

UR - http://www.scopus.com/inward/record.url?scp=84995768055&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84995768055&partnerID=8YFLogxK

U2 - 10.1007/s40257-016-0209-1

DO - 10.1007/s40257-016-0209-1

M3 - Review article

VL - 17

SP - 557

EP - 581

JO - American Journal of Clinical Dermatology

JF - American Journal of Clinical Dermatology

SN - 1175-0561

IS - 6

ER -