Complementary electrical and spectroscopic detection assays with on-wire-lithography-based nanostructures

Gengfeng Zheng; Xiaodong Chen; Chad A. Mirkin

doi:10.1002/smll.200901000

Complementary electrical and spectroscopic detection assays with on-wire-lithography-based nanostructures

Gengfeng Zheng^*, Xiaodong Chen, Chad A. Mirkin

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

On-wire lithography is used to synthesize a new nanostructure composed of a gold-polypyrrole segment and gold nanodisk pairs for parallel electrical and spectroscopic readout (see image). As proof-of-concept, the binding of telo- merase to surface-functionalized oligo- nucleotide receptors and subsequent elongation of the oligonucleotides are demonstrated by parallel electrical and spectroscopic measurements.

Original language	English (US)
Pages (from-to)	2537-2540
Number of pages	4
Journal	Small
Volume	5
Issue number	22
DOIs	https://doi.org/10.1002/smll.200901000
State	Published - Nov 16 2009

Keywords

Biosensors
Nanostructures
On-wire lithography
Surface-enhanced Raman scattering
Telomerase

ASJC Scopus subject areas

General Chemistry
Biotechnology
General Materials Science
Biomaterials

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10.1002/smll.200901000

Cite this

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abstract = "On-wire lithography is used to synthesize a new nanostructure composed of a gold-polypyrrole segment and gold nanodisk pairs for parallel electrical and spectroscopic readout (see image). As proof-of-concept, the binding of telo- merase to surface-functionalized oligo- nucleotide receptors and subsequent elongation of the oligonucleotides are demonstrated by parallel electrical and spectroscopic measurements.",

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AU - Chen, Xiaodong

AU - Mirkin, Chad A.

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KW - Nanostructures

KW - On-wire lithography

KW - Surface-enhanced Raman scattering

KW - Telomerase

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Complementary electrical and spectroscopic detection assays with on-wire-lithography-based nanostructures

Abstract

Keywords

ASJC Scopus subject areas

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