Complementary electrical and spectroscopic detection assays with on-wire-lithography-based nanostructures

Gengfeng Zheng*, Xiaodong Chen, Chad A. Mirkin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

On-wire lithography is used to synthesize a new nanostructure composed of a gold-polypyrrole segment and gold nanodisk pairs for parallel electrical and spectroscopic readout (see image). As proof-of-concept, the binding of telo- merase to surface-functionalized oligo- nucleotide receptors and subsequent elongation of the oligonucleotides are demonstrated by parallel electrical and spectroscopic measurements.

Original languageEnglish (US)
Pages (from-to)2537-2540
Number of pages4
JournalSmall
Volume5
Issue number22
DOIs
StatePublished - Nov 16 2009

Keywords

  • Biosensors
  • Nanostructures
  • On-wire lithography
  • Surface-enhanced Raman scattering
  • Telomerase

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

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