Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA

Olke C. Uhlenbeck; Julie Baller; Paul Doty

doi:10.1038/225508a0

Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA

Olke C. Uhlenbeck^*, Julie Baller, Paul Doty

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

172 Scopus citations

Abstract

Exposed, unpaired areas of an RNA molecule will bind complementary tri and tetranucleotides. The binding can be measured by dialysis equilibrium methods and if the RNA sequence is known the conformation of the molecule can be mapped. The method is here applied to the anticodon loop of formylmethionine tRNA.

Original language	English (US)
Pages (from-to)	508-510
Number of pages	3
Journal	Nature
Volume	225
Issue number	5232
DOIs	https://doi.org/10.1038/225508a0
State	Published - 1970

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title = "Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA",

abstract = "Exposed, unpaired areas of an RNA molecule will bind complementary tri and tetranucleotides. The binding can be measured by dialysis equilibrium methods and if the RNA sequence is known the conformation of the molecule can be mapped. The method is here applied to the anticodon loop of formylmethionine tRNA.",

author = "Uhlenbeck, {Olke C.} and Julie Baller and Paul Doty",

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T1 - Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA

AU - Uhlenbeck, Olke C.

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AU - Doty, Paul

PY - 1970

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AB - Exposed, unpaired areas of an RNA molecule will bind complementary tri and tetranucleotides. The binding can be measured by dialysis equilibrium methods and if the RNA sequence is known the conformation of the molecule can be mapped. The method is here applied to the anticodon loop of formylmethionine tRNA.

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Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA

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