Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device

Jianghong Yuan, Canan Dagdeviren, Yan Shi, Yinji Ma, Xue Feng, John A. Rogers*, Yonggang Huang

*Corresponding author for this work

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Conformal modulus sensors (CMS) incorporate PZT nanoribbons as mechanical actuators and sensors to achieve reversible conformal contact with the human skin for non-invasive, in vivo measurements of skin modulus. An analytic model presented in this paper yields expressions that connect the sensor output voltage to the Young moduli of the epidermis and dermis, the thickness of the epidermis, as well as the material and geometrical parameters of the CMS device itself and its encapsulation layer. Results from the model agree well with in vitro experiments on bilayer structures of poly(dimethylsiloxane). These results provide a means to determine the skin moduli (epidermis and dermis) and the thickness of the epidermis from in vivo measurements of human skin.

Original languageEnglish (US)
Article number20160225
JournalProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume472
Issue number2194
DOIs
StatePublished - Oct 1 2016

Fingerprint

epidermis
Epidermis
Computational Model
Skin
Mechanical Properties
Modulus
mechanical properties
Sensor
Mechanical properties
Dependent
sensors
Sensors
Mechanical actuators
Nanoribbons
Encapsulation
Young's Modulus
Polydimethylsiloxane
Actuator
modulus of elasticity
actuators

Keywords

  • Conformal modulus sensors
  • Electromechanical coupling
  • Epidermis and dermis
  • Skin moduli

ASJC Scopus subject areas

  • Mathematics(all)
  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

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title = "Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device",
abstract = "Conformal modulus sensors (CMS) incorporate PZT nanoribbons as mechanical actuators and sensors to achieve reversible conformal contact with the human skin for non-invasive, in vivo measurements of skin modulus. An analytic model presented in this paper yields expressions that connect the sensor output voltage to the Young moduli of the epidermis and dermis, the thickness of the epidermis, as well as the material and geometrical parameters of the CMS device itself and its encapsulation layer. Results from the model agree well with in vitro experiments on bilayer structures of poly(dimethylsiloxane). These results provide a means to determine the skin moduli (epidermis and dermis) and the thickness of the epidermis from in vivo measurements of human skin.",
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Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device. / Yuan, Jianghong; Dagdeviren, Canan; Shi, Yan; Ma, Yinji; Feng, Xue; Rogers, John A.; Huang, Yonggang.

In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 472, No. 2194, 20160225, 01.10.2016.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Computational models for the determination of depth-dependent mechanical properties of skin with a soft, flexible measurement device

AU - Yuan, Jianghong

AU - Dagdeviren, Canan

AU - Shi, Yan

AU - Ma, Yinji

AU - Feng, Xue

AU - Rogers, John A.

AU - Huang, Yonggang

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AB - Conformal modulus sensors (CMS) incorporate PZT nanoribbons as mechanical actuators and sensors to achieve reversible conformal contact with the human skin for non-invasive, in vivo measurements of skin modulus. An analytic model presented in this paper yields expressions that connect the sensor output voltage to the Young moduli of the epidermis and dermis, the thickness of the epidermis, as well as the material and geometrical parameters of the CMS device itself and its encapsulation layer. Results from the model agree well with in vitro experiments on bilayer structures of poly(dimethylsiloxane). These results provide a means to determine the skin moduli (epidermis and dermis) and the thickness of the epidermis from in vivo measurements of human skin.

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