Concurrent and close temporal administration of lithium and ECT

J. F. Penney, S. H. Dinwiddie, C. F. Zorumski, R. D. Wetzel

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


The clinical effects of concurrent and close temporal administration of electroconvulsive therapy (ECT) and lithium (Li) were investigated by chart review. Three groups of patients were compared on the basis of ECT-related complications, total length of hospital stay (LOS), and post-ECT hospital stay. The groups consisted of patients administered concurrent ECT and Li (n = 27); patients administered Li within 24 h prior to ECT or within 48 h post-ECT (n = 49); and patients administered ECT without concurrent or close temporal administration of Li (n = 100). Prolonged or severe post-ECT confusion was significantly associated with close timing of administration of Li relative to the ECT course. The groups did not differ in the number of complications or the total LOS, although the post-ECT LOS was significantly longer in the group administered Li in close temporal association with ECT. These data suggest that caution should be exercised in the combined use of these treatment modalities.

Original languageEnglish (US)
Pages (from-to)139-145
Number of pages7
JournalConvulsive Therapy
Issue number2
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Psychiatry and Mental health


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