The stepwise synthesis of N, N′, N″-trimethyltetra-anthranilide (13) is reported and the temperature dependence of the1H n.m.r. spectrum of N-benzyl-N, N′, N″, N‴-trimethyltetra-anthranilide (15) is interpreted in terms of equilibration between three diastereoisomeric conformations in solution. Although there is1H n.m.r. spectral evidence for the presence in solution at room temperature of at least six conformational diastereoisomers of (13), N, N″, N‴- tetramethyltetra-anthranilide (14) appears to adopt a single conformation of high symmetry in solution.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of the Chemical Society, Perkin Transactions 1|
|State||Published - 1982|
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