Congenital acquired immunodeficiency syndrome and congenital toxoplasmosis: pathologic support for a chronology of events.

N. E. Cohen-Addad*, V. V. Joshi, L. R. Sharer, L. G. Epstein, T. A. Gubitosi, J. M. Oleske

*Corresponding author for this work

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

We report a case of congenital acquired immunodeficiency syndrome (AIDS) with congenital opportunistic toxoplasmosis. The thymic histopathology was that seen in childhood AIDS cases and not that seen in primary congenital toxoplasmosis. The toxoplasma infection was selectively localized to the brain and the serum titers were paradoxically low as reported in most adult cases of AIDS with secondary infection by the parasite. These findings strongly suggest that the infection by the human immunodeficiency virus (HIV) preceded the toxoplasma infection in the fetus.

Original languageEnglish (US)
Pages (from-to)328-331
Number of pages4
JournalJournal of perinatology : official journal of the California Perinatal Association
Volume8
Issue number4
StatePublished - Sep 1 1988

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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