Congenital lymphocytic choriomeningitis virus—an underdiagnosed fetal teratogen

Michael Kinori; Hal Schwartzstein; Janice Lasky; Sudhi P Kurup; Marilyn B Mets

doi:10.1016/j.jaapos.2017.08.011

Congenital lymphocytic choriomeningitis virus—an underdiagnosed fetal teratogen

Michael Kinori, Hal Schwartzstein, Janice Lasky, Sudhi P Kurup, Marilyn B Mets^*

^*Corresponding author for this work

Ophthalmology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with high mortality and morbidity. Although the number of cases reported in the literature has been increasing, it might still be clinically an underdiagnosed human fetal teratogen. We report 2 more cases of serologically proven congenital LCMV infection. One case presented with Aicardi-like syndrome features. Since congenital LCMV infection may mimic Aicardi syndrome, serologic testing should be considered in the workup of patients with Aicardi syndrome to rule out LCMV infection.

Original language	English (US)
Pages (from-to)	79-81.e1
Journal	Journal of AAPOS
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.jaapos.2017.08.011
State	Published - Feb 1 2018

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jaapos.2017.08.011

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title = "Congenital lymphocytic choriomeningitis virus—an underdiagnosed fetal teratogen",

abstract = "Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with high mortality and morbidity. Although the number of cases reported in the literature has been increasing, it might still be clinically an underdiagnosed human fetal teratogen. We report 2 more cases of serologically proven congenital LCMV infection. One case presented with Aicardi-like syndrome features. Since congenital LCMV infection may mimic Aicardi syndrome, serologic testing should be considered in the workup of patients with Aicardi syndrome to rule out LCMV infection.",

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AU - Schwartzstein, Hal

AU - Lasky, Janice

AU - Kurup, Sudhi P

AU - Mets, Marilyn B

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N2 - Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with high mortality and morbidity. Although the number of cases reported in the literature has been increasing, it might still be clinically an underdiagnosed human fetal teratogen. We report 2 more cases of serologically proven congenital LCMV infection. One case presented with Aicardi-like syndrome features. Since congenital LCMV infection may mimic Aicardi syndrome, serologic testing should be considered in the workup of patients with Aicardi syndrome to rule out LCMV infection.

AB - Congenital lymphocytic choriomeningitis virus (LCMV) infection is associated with high mortality and morbidity. Although the number of cases reported in the literature has been increasing, it might still be clinically an underdiagnosed human fetal teratogen. We report 2 more cases of serologically proven congenital LCMV infection. One case presented with Aicardi-like syndrome features. Since congenital LCMV infection may mimic Aicardi syndrome, serologic testing should be considered in the workup of patients with Aicardi syndrome to rule out LCMV infection.

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Congenital lymphocytic choriomeningitis virus—an underdiagnosed fetal teratogen

Abstract

ASJC Scopus subject areas

UN SDGs

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