Abstract
Affective disorders in people with epilepsy (PWE) have become increasingly recognized as a primary factor in the morbidity and mortality of epilepsy. To improve the recognition and treatment of affective disorders in PWE, an expert panel comprising members from the Epilepsy Foundation's Mood Disorders Initiative have composed a Consensus Statement. This document focuses on depressive disorders in particular and reviews the appearance and treatment of the disorder in children, adolescents, and adults. Idiosyncratic aspects of the appearance of depression in this population, along with physiological and cognitive issues and barriers to treatment, are reviewed. Finally, a suggested approach to the diagnosis of affective disorders in PWE is presented in detail. This includes the use of psychometric tools for diagnosis and a stepwise algorithmic approach to treatment. Recommendations are based on the general depression literature as well as epilepsy-specific studies. It is hoped that this document will improve the overall detection and subsequent treatment of affective illnesses in PWE.
Original language | English (US) |
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Pages (from-to) | S1-S29 |
Journal | Epilepsy and Behavior |
Volume | 13 |
Issue number | SUPPL. 1 |
DOIs | |
State | Published - Jul 2008 |
Funding
The Consensus Statement was developed by the Mood Disorder Advisory Group of the Epilepsy Foundation as part of its Mood Disorder Initiative. The Foundation expresses its deep appreciation to all advisory group members and experts who further contributed to the Consensus Statement. The Epilepsy Foundation also gratefully acknowledges the support of Cyberonics, Inc. for the Mood Disorder Initiative.
Keywords
- Antidepressants
- Anxiety
- Bipolar disorder
- Depression
- Ictal depression
- Interictal depression
- Intractable epilepsy
- Postictal depression
- Suicidality
- Temporal lobe epilepsy
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
- Behavioral Neuroscience