Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

David L. Wyles; Minhee Kang; Roy M. Matining; Robert L. Murphy; Marion G. Peters

doi:10.1093/ofid/ofab511

Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

David L. Wyles^*, Minhee Kang, Roy M. Matining, Robert L. Murphy, Marion G. Peters

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Final results from the long-term Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) found low rates of hepatitis C virus (HCV) recurrence after direct-acting antiviral therapy in both HCV/human immunodeficiency virus (HIV)-coinfected (0.67/100 person-years) and HCV-infected (0.2/100 person-years) groups with >500 person-years of follow-up. Confirmed reinfections were in participants with HIV who reported high-risk behaviors.

Original language	English (US)
Article number	ofab511
Journal	Open Forum Infectious Diseases
Volume	8
Issue number	12
DOIs	https://doi.org/10.1093/ofid/ofab511
State	Published - Dec 1 2021

Funding

Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases, NIH (award numbers UM1 AI068634, UM1 AI068636, UM1 AI106701, and UM1 AI069471).

Keywords

HIV
direct-acting antivirals
hepatitis C
recurrence

ASJC Scopus subject areas

Infectious Diseases
Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Wyles, D. L., Kang, M., Matining, R. M., Murphy, R. L., & Peters, M. G. (2021). Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS). Open Forum Infectious Diseases, 8(12), Article ofab511. https://doi.org/10.1093/ofid/ofab511

Wyles, David L. ; Kang, Minhee ; Matining, Roy M. et al. / Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment : Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS). In: Open Forum Infectious Diseases. 2021 ; Vol. 8, No. 12.

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title = "Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)",

abstract = "Final results from the long-term Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) found low rates of hepatitis C virus (HCV) recurrence after direct-acting antiviral therapy in both HCV/human immunodeficiency virus (HIV)-coinfected (0.67/100 person-years) and HCV-infected (0.2/100 person-years) groups with >500 person-years of follow-up. Confirmed reinfections were in participants with HIV who reported high-risk behaviors.",

keywords = "HIV, direct-acting antivirals, hepatitis C, recurrence",

author = "Wyles, {David L.} and Minhee Kang and Matining, {Roy M.} and Murphy, {Robert L.} and Peters, {Marion G.}",

note = "Funding Information: Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases, NIH (award numbers UM1 AI068634, UM1 AI068636, UM1 AI106701, and UM1 AI069471). Publisher Copyright: {\textcopyright} 2021 The Author(s). Published by Oxford University Press on behalf of Infectious Diseases Society of America.",

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Wyles, DL, Kang, M, Matining, RM, Murphy, RL & Peters, MG 2021, 'Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)', Open Forum Infectious Diseases, vol. 8, no. 12, ofab511. https://doi.org/10.1093/ofid/ofab511

Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS). / Wyles, David L.; Kang, Minhee; Matining, Roy M. et al.
In: Open Forum Infectious Diseases, Vol. 8, No. 12, ofab511, 01.12.2021.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

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AU - Wyles, David L.

AU - Kang, Minhee

AU - Matining, Roy M.

AU - Murphy, Robert L.

AU - Peters, Marion G.

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PY - 2021/12/1

Y1 - 2021/12/1

N2 - Final results from the long-term Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) found low rates of hepatitis C virus (HCV) recurrence after direct-acting antiviral therapy in both HCV/human immunodeficiency virus (HIV)-coinfected (0.67/100 person-years) and HCV-infected (0.2/100 person-years) groups with >500 person-years of follow-up. Confirmed reinfections were in participants with HIV who reported high-risk behaviors.

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KW - recurrence

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Wyles DL, Kang M, Matining RM, Murphy RL, Peters MG. Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS). Open Forum Infectious Diseases. 2021 Dec 1;8(12):ofab511. doi: 10.1093/ofid/ofab511

Continued Low Rates of Hepatitis C Virus (HCV) Recurrence in HCV/HIV-and HCV-Infected Participants Who Achieved Sustained Virologic Response After Direct-Acting Antiviral Treatment: Final Results From the AIDS Clinical Trials Group A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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