Continuous Arrhythmia Monitoring in Pediatric and Adult Patients With Left Ventricular Noncompaction

John L. Jefferies, David S. Spar, A. Sami Chaouki, Philip R. Khoury, Paula Casson, Richard J. Czosek

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with left ventricular noncompaction (LVNC) are at risk of clinically significant arrhythmias and sudden death. We evaluated whether implantable loop recorders could detect significant arrhythmias that might be missed in these patients during annual Holter monitoring. Selected pediatric and adult patients with LVNC who consented to implantable loop recorder placement were monitored for 3 years (study duration, 10 April 2014-9 December 2019). Fourteen subjects were included (age range, 6.5-36.4 yr; 8 males). Of 13 patients who remained after one device extrusion, one underwent implantable cardioverter-defibrillator placement. Four patients (31%) had significant arrhythmias: atrial tachycardia (n=2), nonsustained ventricular tachycardia (n=1), and atrial fibrillation (n=1). All 4 events were clinically asymptomatic and not associated with left ventricular ejection fraction. In addition, a high frequency of benign arrhythmic patterns was detected. Implantable loop recorders enable continuous, long-term detection of important subclinical arrhythmias in selected patients who have LVNC. These devices may prove to be most valuable in patients who have LVNC and moderate or greater ventricular dysfunction.

Original languageEnglish (US)
JournalTexas Heart Institute Journal
Volume49
Issue number2
DOIs
StatePublished - Mar 1 2022
Externally publishedYes

Keywords

  • Arrhythmias, cardiac/diagnosis/prevention & control/therapy
  • cardiomyopathies/pathology
  • electrocardiography, ambulatory
  • electrophysiologic techniques, cardiac/methods
  • heart function tests
  • isolated noncompaction of the ventricular myocardium/complications
  • monitoring, physiologic/methods
  • risk assessment/methods

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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