Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

Xuejin Li, Petia M. Vlahovska, George Em Karniadakis*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

93 Scopus citations

Abstract

We review recent advances in multiscale modeling of the mechanics of healthy and diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the traditional continuum-based methods but also particle-based methods used to model both the RBCs and the blood plasma. We highlight examples of successful simulations of blood flow including malaria and sickle cell anemia.

Original languageEnglish (US)
Pages (from-to)28-37
Number of pages10
JournalSoft Matter
Volume9
Issue number1
DOIs
StatePublished - Jan 7 2013

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics

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