Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

Xuejin Li; Petia M. Vlahovska; George Em Karniadakis

doi:10.1039/c2sm26891d

Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

Xuejin Li, Petia M. Vlahovska, George Em Karniadakis^*

^*Corresponding author for this work

Engineering Sciences and Applied Mathematics

Research output: Contribution to journal › Review article › peer-review

93 Scopus citations

Abstract

We review recent advances in multiscale modeling of the mechanics of healthy and diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the traditional continuum-based methods but also particle-based methods used to model both the RBCs and the blood plasma. We highlight examples of successful simulations of blood flow including malaria and sickle cell anemia.

Original language	English (US)
Pages (from-to)	28-37
Number of pages	10
Journal	Soft Matter
Volume	9
Issue number	1
DOIs	https://doi.org/10.1039/c2sm26891d
State	Published - Jan 7 2013

ASJC Scopus subject areas

Chemistry(all)
Condensed Matter Physics

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