Contraception, fecundity, and pregnancy in women with epilepsy: An update on recent literature

Alexa King, Elizabeth E. Gerard*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of reviewCaring for women with epilepsy requires specialized knowledge about potential teratogenicity of antiseizure medications, interactions with hormonal contraception, and pregnancy outcomes.Recent findingsThere has been an improvement in understanding the cognitive outcomes of infants exposed in utero in recent years. Folic acid supplementation helps mitigate the cognitive teratogenicity of antiseizure medications. Recent updates provide reassurance that seizure frequency tends to remain stable throughout pregnancy. There is conflicting evidence about the fecundity impact of epilepsy and antiseizure medications in women with epilepsy.SummaryRecent research highlights the importance of early counseling about the risks and interactions of contraception, pregnancy, and antiseizure medications. More research is needed to understand fertility in women with epilepsy.

Original languageEnglish (US)
Pages (from-to)161-168
Number of pages8
JournalCurrent Opinion in Neurology
Volume35
Issue number2
DOIs
StatePublished - Apr 1 2022

Keywords

  • contraception
  • fertility
  • pregnancy
  • women with epilepsy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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