Contralateral acoustic stimulation alters the magnitude and phase of distortion product otoacoustic emissions

Ryan Deeter; Rebekah Abel; Lauren Calandruccio; Sumitrajit Dhar

doi:10.1121/1.3224716

Contralateral acoustic stimulation alters the magnitude and phase of distortion product otoacoustic emissions

Ryan Deeter, Rebekah Abel, Lauren Calandruccio, Sumitrajit Dhar^*

^*Corresponding author for this work

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Abstract

Activation of medial olivocochlear efferents through contralateral acoustic stimulation (CAS) has been shown to modulate distortion product otoacoustic emission (DPOAE) level in various ways (enhancement, reduction, or no change). The goal of this study was to investigate the effect of a range of CAS levels on DPOAE fine structure. The 2 f₁ - f₂ DPOAE was recorded (f₂ / f₁ =1.22, L₁ =55 dB, and L₂ =40 dB) from eight normal-hearing subjects, using both a frequency-sweep paradigm and a fixed frequency paradigm. Contamination due to the middle ear muscle reflex was avoided by monitoring the magnitude and phase of a probe in the test ear and by monitoring DPOAE stimulus levels throughout testing. Results show modulations in both level and frequency of DPOAE fine structure patterns. Frequency shifts observed at DPOAE level minima could explain reports of enhancement in DPOAE level due to efferent activation. CAS affected the magnitude and phase of the DPOAE component from the characteristic frequency region to a greater extent than the component from the overlap region between the stimulus tones. This differential effect explains the occasional enhancement observed in DPOAE level as well as the frequency shift in fine structure patterns.

Original language	English (US)
Pages (from-to)	2413-2424
Number of pages	12
Journal	journal of the Acoustical Society of America
Volume	126
Issue number	5
DOIs	https://doi.org/10.1121/1.3224716
State	Published - 2009

Funding

We would like to thank Dashiell Oatman-Stanford and Deepika Sriram for assistance with data collection. Helpful discussions with Wei Zhao, Renee Banakis, Hwa Jung Son, Mead Killion, Carolina Abdala, and Jonathan Siegel shaped our thinking about the issues presented here. This research was funded by Grant Nos. R01DC008420 and R01DC003552 (subcontract to Northwestern from the House Ear Institute) from the NIDCD, and the Hugh Knowles Center for Hearing Research at Northwestern University. Parts of this work were presented at the 2009 Annual Convention of the American Auditory Society.

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Acoustics and Ultrasonics

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10.1121/1.3224716

Cite this

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title = "Contralateral acoustic stimulation alters the magnitude and phase of distortion product otoacoustic emissions",

abstract = "Activation of medial olivocochlear efferents through contralateral acoustic stimulation (CAS) has been shown to modulate distortion product otoacoustic emission (DPOAE) level in various ways (enhancement, reduction, or no change). The goal of this study was to investigate the effect of a range of CAS levels on DPOAE fine structure. The 2 f1 - f2 DPOAE was recorded (f2 / f1 =1.22, L1 =55 dB, and L2 =40 dB) from eight normal-hearing subjects, using both a frequency-sweep paradigm and a fixed frequency paradigm. Contamination due to the middle ear muscle reflex was avoided by monitoring the magnitude and phase of a probe in the test ear and by monitoring DPOAE stimulus levels throughout testing. Results show modulations in both level and frequency of DPOAE fine structure patterns. Frequency shifts observed at DPOAE level minima could explain reports of enhancement in DPOAE level due to efferent activation. CAS affected the magnitude and phase of the DPOAE component from the characteristic frequency region to a greater extent than the component from the overlap region between the stimulus tones. This differential effect explains the occasional enhancement observed in DPOAE level as well as the frequency shift in fine structure patterns.",

author = "Ryan Deeter and Rebekah Abel and Lauren Calandruccio and Sumitrajit Dhar",

note = "Funding Information: We would like to thank Dashiell Oatman-Stanford and Deepika Sriram for assistance with data collection. Helpful discussions with Wei Zhao, Renee Banakis, Hwa Jung Son, Mead Killion, Carolina Abdala, and Jonathan Siegel shaped our thinking about the issues presented here. This research was funded by Grant Nos. R01DC008420 and R01DC003552 (subcontract to Northwestern from the House Ear Institute) from the NIDCD, and the Hugh Knowles Center for Hearing Research at Northwestern University. Parts of this work were presented at the 2009 Annual Convention of the American Auditory Society.",

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Contralateral acoustic stimulation alters the magnitude and phase of distortion product otoacoustic emissions

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