Contrast Nephrotoxicity

M. Bursztyn, V. J. Canzannello, F. A. Eames, B. J. Barrett, P. S. Parfrey, S. M. Griffiths, S. J. Schwab, M. A. Hlatky, K. S. Pieper, C. J. Davidson, K. G. Morris, T. M. Bashore, T. N. Skelton

Research output: Contribution to journalLetter

2 Scopus citations

Abstract

To the Editor: Neither the two papers on contrast medium–induced nephrotoxicity (Jan. 19 issue)12 nor the accompanying editorial3 took into account the possible influence of drug therapy (particularly, treatment with calcium-channel blockers or furosemide). The editorial3 stated that contrast medium–induced renal vasoconstriction could cause hypoxia in the renal medulla (the part of the kidney most vulnerable to ischemia), and that this effect may be central to the resulting nephrotoxicity. It is now well recognized that calcium antagonists may alter such injurious effects.4 They are potent renal vasodilators, particularly when renal vascular tone is increased.5 Moreover, these agents may redistribute renal.

Original languageEnglish (US)
Pages (from-to)395-397
Number of pages3
JournalNew England Journal of Medicine
Volume321
Issue number6
DOIs
StatePublished - Aug 10 1989

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Contrast Nephrotoxicity'. Together they form a unique fingerprint.

  • Cite this

    Bursztyn, M., Canzannello, V. J., Eames, F. A., Barrett, B. J., Parfrey, P. S., Griffiths, S. M., Schwab, S. J., Hlatky, M. A., Pieper, K. S., Davidson, C. J., Morris, K. G., Bashore, T. M., & Skelton, T. N. (1989). Contrast Nephrotoxicity. New England Journal of Medicine, 321(6), 395-397. https://doi.org/10.1056/NEJM198908103210614