Contrast suppression

Gregory William Schwartz*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Any introduction to visual neuroscience will mention three polarities of visual neurons: ON, OFF, and ON-OFF. However, a fourth polarity class, called suppressed-by-contrast (SbC) cells, whose baseline firing rate is reduced for both positive and negative contrasts, has traditionally received less attention. In 2015, the discovery of SbC cells in the mouse retina initiated a dramatic acceleration of work on these circuits, revealing an impressive array of different mechanisms in different cell types. There has also been a renewed interest in how SbC information from the retina is used in the brain.

Original languageEnglish (US)
Title of host publicationRetinal Computation
Number of pages22
ISBN (Print)9780128198964
StatePublished - Aug 17 2021


  • Contrast suppression
  • Retina
  • SbC RGC
  • Suppressed-by-contrast
  • Uniformity detector

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


Dive into the research topics of 'Contrast suppression'. Together they form a unique fingerprint.

Cite this