Contrasting disease and nondisease protein aggregation by molecular simulation

Keyphrases

• Protein Aggregation 100%
• Molecular Simulation 100%
• Disease-related Proteins 66%
• Functional State 66%
• Protein Sequence 66%
• Inclusion Bodies 66%
• Folding Intermediate 66%
• Alzheimer 33%
• Native State 33%
• Molecular Mechanism 33%
• Computational Model 33%
• Peptide Sequencing 33%
• Molecular Properties 33%
• Protective Behavior 33%
• High Concentration 33%
• Solution Conditions 33%
• Amyloid Protein 33%
• Testable Hypothesis 33%
• Large Aggregates 33%
• Protein Production 33%
• Range Order 33%
• Amyloid Fibrils 33%
• Amorphous Structure 33%
• Amyloidosis 33%
• Aggregate Morphology 33%
• Experimen 33%
• Fibrillar Aggregates 33%
• Protein Concentration 33%
• Virulence Variation 33%
• Denatured State Ensemble 33%
• Early Aggregation 33%
• Protein Solution 33%
• Oligomeric Structure 33%
• Kinetic Assay 33%
• Industrial Proteins 33%
• Critical nucleus 33%
• Experimental Observable 33%
• Familial Alzheimer's Disease 33%
• Aggregation Mechanism 33%
• Binding Kinetics 33%
• Dye Binding 33%
• Fibril Assembly 33%
• Peptide Concentration 33%
• Amorphous Inclusion 33%
• Polymerization Mechanism 33%
• Oligomeric Aggregates 33%
• Cross-order 33%
• Free Energy Barrier 33%
• Fibril Polymorphism 33%
• Molecular Aggregation 33%
• Intrachain Contact 33%

Biochemistry, Genetics and Molecular Biology

• Protein Aggregation 100%
• Amyloid Protein 100%
• Peptide Sequence 60%
• Protein L 40%
• Protein G 40%
• Solution and Solubility 20%
• Denatured State 20%
• Binding Kinetics 20%