Contrasting effects of IFNβ and IVIG in children with central and peripheral demyelination

I. Pirko, N. L. Kuntz, M. Patterson, B. M. Keegan, B. G. Weinshenker, M. Rodriguez*

*Corresponding author for this work

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Reported are three children with MS who responded dramatically to interferon-β (IFNβ) therapy. While on immunomodulatory therapy, they developed chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) that responded to IV immunoglobulin (IVIG) administration. These cases emphasize two interesting observations: 1) IFNβ treatment did not prevent development of CIDP; 2) CIDP in the context of MS responded to IVIG, even though IVIG had no therapeutic effect on the central demyelinating disease.

Original languageEnglish (US)
Pages (from-to)1697-1699
Number of pages3
JournalNeurology
Volume60
Issue number10
DOIs
StatePublished - May 27 2003

ASJC Scopus subject areas

  • Clinical Neurology

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