Control of nanoparticle assembly by using DNA-modified diatom templates

Nathaniel L. Rosi; C. Shad Thaxton; Chad A. Mirkin

doi:10.1002/anie.200460905

Control of nanoparticle assembly by using DNA-modified diatom templates

Nathaniel L. Rosi, C. Shad Thaxton, Chad A. Mirkin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

135 Scopus citations

Abstract

Microorganisms point the way: The silica cell walls of various diatoms were covalently functionalized with DNA by using straightforward chemical procedures and then used as templates for the sequence-specific assembly and 3D hierarchical arrangement of prefabricated DNA-modified gold nanoparticles. The DNA was used to further direct the assembly of multiple nanoparticle layers onto the diatom templates (see picture).

Original language	English (US)
Pages (from-to)	5500-5503
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	43
Issue number	41
DOIs	https://doi.org/10.1002/anie.200460905
State	Published - Oct 18 2004

Keywords

DNA
Microorganism
Nanostructures
Self-assembly
Template synthesis

ASJC Scopus subject areas

Chemistry(all)

Access to Document

10.1002/anie.200460905

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