Controlling epileptiform activity with organic electronic ion pumps

Adam Williamson, Jonathan Rivnay, Loïg Kergoat, Amanda Jonsson, Sahika Inal, Ilke Uguz, Marc Ferro, Anton Ivanov, Theresia Arbring Sjöström, Daniel T. Simon, Magnus Berggren, George G. Malliaras*, Christophe Bernard

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

85 Scopus citations

Abstract

In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.

Original languageEnglish (US)
Pages (from-to)3138-3144
Number of pages7
JournalAdvanced Materials
Volume27
Issue number20
DOIs
StatePublished - May 1 2015

Keywords

  • PEDOT:PSS
  • neuroengineering
  • organic bioelectronics
  • organic electronic ion pumps

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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