Abstract
Influenza A and viruses encode minimalistic proton-selective ion channels known as A/M2 and BM2, respectively. The A/M2 channel is the target of the antiviral drug, amantadine. The structural and mechanistic aspects of proton conductance of the viral ion channels are described and the review makes a case for the development of more effective antivirals.
Original language | English (US) |
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Pages (from-to) | 18-23 |
Number of pages | 6 |
Journal | Molecular bioSystems |
Volume | 3 |
Issue number | 1 |
DOIs | |
State | Published - 2007 |
ASJC Scopus subject areas
- Biotechnology
- Molecular Biology