Coordination and localization in spinal motor systems

Matthew C. Tresch, Philippe Saltiel, Andrea D'Avella, Emilio Bizzi*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

125 Scopus citations


We review here experiments examining the hypothesis that vertebrate spinal motor systems produce movement through the flexible combination of a small number of units of motor output. Using a variety of preparations and techniques, these experiments provide evidence for such spinally generated units and for the localization of the networks responsible for producing them within different regions of the spinal cord. Such an organization might help to simplify the production of movement, reducing the degrees of freedom that need to be specified by providing a set of units involved in regulating features common to a range of behaviors.

Original languageEnglish (US)
Pages (from-to)66-79
Number of pages14
JournalBrain Research Reviews
Issue number1-3
StatePublished - Oct 2002


  • Central pattern generator
  • Modularity
  • Motor control
  • Spinal cord
  • Spinal interneuron
  • Synergy

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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