COQ6 defies immune and metabolic expectations

Sam E Weinberg; Navdeep S. Chandel

doi:10.1038/s41590-024-02005-6

COQ6 defies immune and metabolic expectations

Sam E Weinberg, Navdeep S. Chandel^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

A COQ6 variant increases susceptibility to pneumococcal infection via non-bone marrow-derived cells without affecting ubiquinone synthesis, challenging traditional views on the metabolic role of COQ6 role and opening new avenues for understanding immunometabolic interactions.

Original language	English (US)
Pages (from-to)	2170-2172
Number of pages	3
Journal	Nature Immunology
Volume	25
Issue number	12
DOIs	https://doi.org/10.1038/s41590-024-02005-6
State	Published - Dec 2024

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1038/s41590-024-02005-6

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title = "COQ6 defies immune and metabolic expectations",

abstract = "A COQ6 variant increases susceptibility to pneumococcal infection via non-bone marrow-derived cells without affecting ubiquinone synthesis, challenging traditional views on the metabolic role of COQ6 role and opening new avenues for understanding immunometabolic interactions.",

author = "Weinberg, {Sam E} and Chandel, {Navdeep S.}",

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year = "2024",

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doi = "10.1038/s41590-024-02005-6",

language = "English (US)",

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JO - Nature Immunology

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COQ6 defies immune and metabolic expectations

Abstract

ASJC Scopus subject areas

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