Cordocentesis: An appraisal of risks

Bruce W. Pielet*, Michael L. Socol, Scott N. MacGregor, Judith A. Ney, Sharon L. Dooley

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Fetal blood sampling via cordocentesis is being used with increasing frequency. Between March 1986 and February 1988, we performed 58 intravascular transfusions (64 attempts) and 27 fetal blood samplings (28 attempts) guided by ultrasonography. The complication rates for intravascular transfusion and fetal blood sampling were 9.4% (6 of 64) and 7.1% (2 of 28), respectively. The procedure-related mortality rates were 4.7% (3 of 64) and 0%. We caution that the potential complications be seriously considered when appropriate patients are selected for cordocentesis. Additionally, we recommend that cordocentesis be performed only in tertiary care centers by personnel skilled in both ultrasonography and prenatal diagnosis.

Original languageEnglish (US)
Pages (from-to)1497-1500
Number of pages4
JournalAmerican journal of obstetrics and gynecology
Issue number6
StatePublished - Dec 1988


  • Cordocentesis
  • complications
  • fetal blood sampling
  • fetal intravascular transfusion

ASJC Scopus subject areas

  • Obstetrics and Gynecology


Dive into the research topics of 'Cordocentesis: An appraisal of risks'. Together they form a unique fingerprint.

Cite this