Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain

Lisa M. Neff*, Mindy E. Hoffmann, Dinah M. Zeiss, Katherine Lowry, Monica Edwards, Sarah M. Rodriguez, Kelley N. Wachsberg, Robert Kushner, Lewis Landsberg

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations


Objective Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature. Methods Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperature sensor. Results The mean 24-h core body temperature was 0.25±0.06°C lower in postmenopausal than premenopausal women (P=0.001). The mean 24 h core temperature was 0.34±0.05°C lower in men than in premenopausal women (P<0.001). Conclusion Postmenopausal women, like men, had lower core body temperatures than premenopausal women. This may have implications for midlife weight gain.

Original languageEnglish (US)
Pages (from-to)151-154
Number of pages4
JournalCardiovascular Endocrinology
Issue number4
StatePublished - Nov 1 2016



  • Keywords: menopause
  • metabolism
  • obesity
  • temperature
  • weight
  • women

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrine and Autonomic Systems
  • Cardiology and Cardiovascular Medicine

Cite this