Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain

Lisa M Neff; Mindy E. Hoffmann; Dinah M. Zeiss; Katherine Lowry; Monica Edwards; Sarah M. Rodriguez; Kelley N. Wachsberg; Robert Kushner; Lewis Landsberg

doi:10.1097/XCE.0000000000000078

Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain

Lisa M Neff^*, Mindy E. Hoffmann, Dinah M. Zeiss, Katherine Lowry, Monica Edwards, Sarah M. Rodriguez, Kelley N. Wachsberg, Robert Kushner, Lewis Landsberg

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Objective Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature. Methods Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperature sensor. Results The mean 24-h core body temperature was 0.25±0.06°C lower in postmenopausal than premenopausal women (P=0.001). The mean 24 h core temperature was 0.34±0.05°C lower in men than in premenopausal women (P<0.001). Conclusion Postmenopausal women, like men, had lower core body temperatures than premenopausal women. This may have implications for midlife weight gain.

Original language	English (US)
Pages (from-to)	151-154
Number of pages	4
Journal	Cardiovascular Endocrinology
Volume	5
Issue number	4
DOIs	https://doi.org/10.1097/XCE.0000000000000078
State	Published - Nov 1 2016

Funding

The Joseph and Bessie Feinberg Foundation and David Kabiller, the project described was supported, in part, by the Northwestern University Clinical and Translational Science Institute, Grant Number UL1TR000150 from the National Center for Advancing Translational Sciences, Clinical and Translational Sciences Award, and by the National Center for Research Resources, Grant Number UL1RR025741. The content is solely the responsibility of the authors (LMN, MEH, LL) and does not necessarily represent the official views of the NIH. The Clinical and Translational Science Award (CTSA) is a registered trademark of the U.S. Department of Health and Human Services (DHHS).

Keywords

Keywords: menopause
metabolism
obesity
temperature
weight
women

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrine and Autonomic Systems
Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/XCE.0000000000000078

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Neff, L. M., Hoffmann, M. E., Zeiss, D. M., Lowry, K., Edwards, M., Rodriguez, S. M., Wachsberg, K. N., Kushner, R., & Landsberg, L. (2016). Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain. Cardiovascular Endocrinology, 5(4), 151-154. https://doi.org/10.1097/XCE.0000000000000078

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title = "Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain",

abstract = "Objective Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature. Methods Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperature sensor. Results The mean 24-h core body temperature was 0.25±0.06°C lower in postmenopausal than premenopausal women (P=0.001). The mean 24 h core temperature was 0.34±0.05°C lower in men than in premenopausal women (P<0.001). Conclusion Postmenopausal women, like men, had lower core body temperatures than premenopausal women. This may have implications for midlife weight gain.",

keywords = "Keywords: menopause, metabolism, obesity, temperature, weight, women",

author = "Neff, {Lisa M} and Hoffmann, {Mindy E.} and Zeiss, {Dinah M.} and Katherine Lowry and Monica Edwards and Rodriguez, {Sarah M.} and Wachsberg, {Kelley N.} and Robert Kushner and Lewis Landsberg",

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Neff, LM, Hoffmann, ME, Zeiss, DM, Lowry, K, Edwards, M, Rodriguez, SM, Wachsberg, KN , Kushner, R & Landsberg, L 2016, 'Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain', Cardiovascular Endocrinology, vol. 5, no. 4, pp. 151-154. https://doi.org/10.1097/XCE.0000000000000078

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T1 - Core body temperature is lower in postmenopausal women than premenopausal women

T2 - Potential implications for energy metabolism and midlife weight gain

AU - Neff, Lisa M

AU - Hoffmann, Mindy E.

AU - Zeiss, Dinah M.

AU - Lowry, Katherine

AU - Edwards, Monica

AU - Rodriguez, Sarah M.

AU - Wachsberg, Kelley N.

AU - Kushner, Robert

AU - Landsberg, Lewis

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Objective Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature. Methods Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperature sensor. Results The mean 24-h core body temperature was 0.25±0.06°C lower in postmenopausal than premenopausal women (P=0.001). The mean 24 h core temperature was 0.34±0.05°C lower in men than in premenopausal women (P<0.001). Conclusion Postmenopausal women, like men, had lower core body temperatures than premenopausal women. This may have implications for midlife weight gain.

AB - Objective Weight gain during the menopausal transition is common. Although studies have suggested that weight gain is more likely related to aging than menopause, there is a reduction in resting energy expenditure with surgical or natural menopause that is independent of age and changes in body composition. The underlying mechanisms could include a reduction in core body temperature. Methods Data were obtained from two related studies. Sample size was 23 men and 25 women (12 premenopausal, 13 postmenopausal). In the Clinical Research Unit, core temperature was measured every minute for 24 h using an ingested temperature sensor. Results The mean 24-h core body temperature was 0.25±0.06°C lower in postmenopausal than premenopausal women (P=0.001). The mean 24 h core temperature was 0.34±0.05°C lower in men than in premenopausal women (P<0.001). Conclusion Postmenopausal women, like men, had lower core body temperatures than premenopausal women. This may have implications for midlife weight gain.

KW - Keywords: menopause

KW - metabolism

KW - obesity

KW - temperature

KW - weight

KW - women

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Core body temperature is lower in postmenopausal women than premenopausal women: Potential implications for energy metabolism and midlife weight gain

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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