Correlates of PrEP Indication in a Multi-Site Cohort of Young HIV-Uninfected Transgender Women

Lisa M. Kuhns*, Sari L. Reisner, Matthew J. Mimiaga, Travis Gayles, Michael Shelendich, Robert Garofalo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Transgender women are at high risk of HIV infection, with younger transgender women (YTW) particularly vulnerable. Pre-Exposure Prophylaxis (PrEP) has shown efficacy in reducing HIV acquisition, but little is known about PrEP indication or initiation among YTW. Baseline data from 180 YTW age 18–29 years enrolled in Project LifeSkills, an on-going HIV prevention intervention for YTW, were analyzed to examine factors associated with PrEP indication. The sample (mean age = 23.4, SD = 3.2) was comprised largely of women of color (69 %) and of low socioeconomic status (71 % unemployed). Overall, 62 % met criteria for PrEP indication, but only 5 % reported ever taking PrEP. Factors associated with increased odds of PrEP indication were: PrEP interest (aOR 3.24; 95 % CI 1.44, 7.33), number of recent anal sex partners (aOR 1.23; 95 % CI 1.04, 1.46), and lower collective self-esteem scores (aOR 0.67; 95 % CI 0.47, 0.94). Despite high levels of PrEP indication, there remain low levels of PrEP awareness and uptake among YTW.

Original languageEnglish (US)
Pages (from-to)1470-1477
Number of pages8
JournalAIDS and behavior
Issue number7
StatePublished - Jul 1 2016


  • HIV
  • PrEP
  • Transgender
  • Young adults

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Social Psychology


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