Correlation between isometric force and intramuscular pressure in rabbit tibialis anterior muscle with an intact anterior compartment

Taylor M. Winters, Genaro S. Sepulveda, Patrick S. Cottler, Kenton R. Kaufman, Richard L. Lieber, Samuel R. Ward

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

To determine the degree to which intramuscular pressure (IMP) and muscle force are correlated in an intact compartment, a custom pressure transducer was inserted into the rabbit tibialis anterior (TA) while activating the muscle via the peroneal nerve and measuring TA muscle force distal to the ankle retinaculum. In general, IMP was more variable compared with muscle force throughout the entire isometric length-tension relationship. In contrast to results obtained on isolated TA muscles, IMP-force relations with the compartment intact were not significantly different between the ascending and descending limbs of the length-tension curve. Specifically, average relative pressure-force coefficients of determination (r2) were 0.76 ± 0.11 for the active ascending limb and 0.98 ± 0.01 for the active descending limb. These data demonstrate that muscle force and IMP are fairly well correlated under isometric conditions and that this relationship is not improved by measuring IMP in an intact environment.

Original languageEnglish (US)
Pages (from-to)79-85
Number of pages7
JournalMuscle and Nerve
Volume40
Issue number1
DOIs
StatePublished - Jul 1 2009

Keywords

  • Fluid mechanics
  • Fluid pressure
  • Intramuscular pressure
  • Isometric contraction
  • Length-tension relationship

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Correlation between isometric force and intramuscular pressure in rabbit tibialis anterior muscle with an intact anterior compartment'. Together they form a unique fingerprint.

  • Cite this