Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations

Ramesh C. Arora; Suman Sahai; Herbert Y. Meltzer

doi:10.1016/0165-1781(83)90102-6

Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations

Ramesh C. Arora, Suman Sahai, Herbert Y. Meltzer^*

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Monoamine oxidase (MAO) activity in human blood platelets isolated by a single centrifugation at 600g for 2 1 2 minutes, which isolates only 45-65% of total platelets, was highly correlated with the MAO activity in platelets isolated by a method which isolates essentially 100% of platelets (r = 0.95, p < 0.01). These results indicate that the single centrifugation method, which isolates only a portion of platelets, gives a reliable estimate of MAO activity in the entire platelet population.

Original language	English (US)
Pages (from-to)	147-151
Number of pages	5
Journal	Psychiatry Research
Volume	8
Issue number	2
DOIs	https://doi.org/10.1016/0165-1781(83)90102-6
State	Published - Feb 1983

Keywords

Corash method
Monoamine oxidase (MAO)
differential centrifugation
platelet

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-1781(83)90102-6

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title = "Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations",

abstract = "Monoamine oxidase (MAO) activity in human blood platelets isolated by a single centrifugation at 600g for 2 1 2 minutes, which isolates only 45-65% of total platelets, was highly correlated with the MAO activity in platelets isolated by a method which isolates essentially 100% of platelets (r = 0.95, p < 0.01). These results indicate that the single centrifugation method, which isolates only a portion of platelets, gives a reliable estimate of MAO activity in the entire platelet population.",

keywords = "Corash method, Monoamine oxidase (MAO), differential centrifugation, platelet",

author = "Arora, {Ramesh C.} and Suman Sahai and Meltzer, {Herbert Y.}",

note = "Funding Information: Acknowledgment. The research reported was supported, in part, by USPHS 25116 and MH-30938. HYM is recipient of USPHS RCSA MH-47808.",

year = "1983",

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doi = "10.1016/0165-1781(83)90102-6",

language = "English (US)",

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journal = "Psychiatry Research",

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T1 - Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations

AU - Arora, Ramesh C.

AU - Sahai, Suman

AU - Meltzer, Herbert Y.

N1 - Funding Information: Acknowledgment. The research reported was supported, in part, by USPHS 25116 and MH-30938. HYM is recipient of USPHS RCSA MH-47808.

PY - 1983/2

Y1 - 1983/2

N2 - Monoamine oxidase (MAO) activity in human blood platelets isolated by a single centrifugation at 600g for 2 1 2 minutes, which isolates only 45-65% of total platelets, was highly correlated with the MAO activity in platelets isolated by a method which isolates essentially 100% of platelets (r = 0.95, p < 0.01). These results indicate that the single centrifugation method, which isolates only a portion of platelets, gives a reliable estimate of MAO activity in the entire platelet population.

AB - Monoamine oxidase (MAO) activity in human blood platelets isolated by a single centrifugation at 600g for 2 1 2 minutes, which isolates only 45-65% of total platelets, was highly correlated with the MAO activity in platelets isolated by a method which isolates essentially 100% of platelets (r = 0.95, p < 0.01). These results indicate that the single centrifugation method, which isolates only a portion of platelets, gives a reliable estimate of MAO activity in the entire platelet population.

KW - Corash method

KW - Monoamine oxidase (MAO)

KW - differential centrifugation

KW - platelet

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AN - SCOPUS:0020685051

SN - 0165-1781

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JO - Psychiatry Research

JF - Psychiatry Research

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ER -

Correlation between MAO activity in blood platelets obtained by single and multiple centrifugations

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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