Correlations among cutaneous reactivity to DNCB, PHA induced lymphocyte blastogenesis and peripheral blood E rosettes

W. J. Catalona, J. L. Tarpley, C. Potvin, P. B. Chretien

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Comparisons of the results obtained in a study of 52 patients with genito urinary malignancies using 3 assays to monitor the thymus dependent immune system (delayed cutaneous hypersensitivity to DNCB, PHA induced lymphocyte blastogenesis, and peripheral blood E rosette forming lymphocyte counts) yielded statistically significant positive correlations between the DNCB and PHA assays in 21 of 28 instances, the DNCB and E rosette assays in 13 of 16 instances, the PHA and E rosette assays in 28 of 36 instances, and among the DNCB, PHA and E rosette assays in 10 of 14 instances. The results suggest that both PHA stimulated lymphocyte blastogenesis and peripheral blood E rosette forming lymphocyte levels provide meaningful in vitro correlates of cell mediated immunity.

Original languageEnglish (US)
Pages (from-to)327-333
Number of pages7
JournalClinical and Experimental Immunology
Volume19
Issue number2
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'Correlations among cutaneous reactivity to DNCB, PHA induced lymphocyte blastogenesis and peripheral blood E rosettes'. Together they form a unique fingerprint.

Cite this