Comparisons of the results obtained in a study of 52 patients with genito urinary malignancies using 3 assays to monitor the thymus dependent immune system (delayed cutaneous hypersensitivity to DNCB, PHA induced lymphocyte blastogenesis, and peripheral blood E rosette forming lymphocyte counts) yielded statistically significant positive correlations between the DNCB and PHA assays in 21 of 28 instances, the DNCB and E rosette assays in 13 of 16 instances, the PHA and E rosette assays in 28 of 36 instances, and among the DNCB, PHA and E rosette assays in 10 of 14 instances. The results suggest that both PHA stimulated lymphocyte blastogenesis and peripheral blood E rosette forming lymphocyte levels provide meaningful in vitro correlates of cell mediated immunity.
|Original language||English (US)|
|Number of pages||7|
|Journal||Clinical and Experimental Immunology|
|State||Published - Dec 1 1975|
ASJC Scopus subject areas
- Immunology and Allergy