Correlations between akathisia and residual psychopathology: A by-product of neuroleptic-induced dysphoria

J. W. Newcomer*, L. S. Miller, W. O. Faustman, M. W. Wetzel, G. P. Vogler, J. G. Csernansky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Patients developing neuroleptic-induced akathisia have been reported to show higher levels of psychopathology. We sought to replicate this finding and determine its symptom specificity. We confirmed a significant relationship between ratings of akathisia and total score on the Brief Psychiatric Rating Scale (BPRS) during both acute and maintenance neuroleptic treatment. Using stepwise regression models, BPRS anxious-depressive subscale scores were the strongest predictors of akathisia during both treatment conditions. Paranoid subscale scores predicted akathisia only during maintenance treatment. These results suggest that neuroleptic-induced dysphoria largely explains the relationship between akathisia and residual psychopathology during both acute and maintenance neuroleptic treatment.

Original languageEnglish (US)
Pages (from-to)834-838
Number of pages5
JournalBritish Journal of Psychiatry
Volume164
Issue numberJUNE
DOIs
StatePublished - 1994

ASJC Scopus subject areas

  • Psychiatry and Mental health

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